Andrew McCulloch
External collaborator
Publications
Simula-affiliated publications listed
2023
Journal Articles
M. T. Hock, A. Teitgen, K. J. McCabe, S. P. Hirakis, G. Huber, M. Regnier, R. E. Amaro, A. J. McCammon and A. D. McCulloch
Multiscale computational modeling of the effects of 2’-deoxy-ATP on cardiac muscle calcium handling
Journal of Applied Physics
2022
Talks, contributed
L. Pankewitz, S. Govil, K. G. Hustad, J. C. Perry, S. Hedge, R. Tang, A. D. McCulloch and H. Arevalo
Development of a Biventricular Coordinate System with Representation of an Anatomically Detailed Base
Tampere
2021
Book Chapters
A. G. Edwards, J. van den Brink and A. D. McCulloch
Calcium Signaling in Cardiomyocyte Models With Realistic Geometries
Zipes and Jalife's Cardiac Electrophysiology: From Cell to Bedside
2020
Journal Articles
V. Timmermann, A. T. Quinn, J. Sundnes, S. Wall, A. D. McCulloch and A. G. Edwards
A computational study on integrated mechanisms of mechano-electric feedback in ischemic arrhythmogenesis
SAGE
V. Timmermann and A. D. McCulloch
Mechano-electric coupling and arrhythmogenic current generation in a computational model of coupled myocytes
Frontiers in physiology
K. J. McCabe, Y. Aboelkassem, A. Teitgen, G. Huber, A. J. McCammon, M. Regnier and A. D. McCulloch
Predicting the effects of dATP on cardiac contraction using multiscale modeling of the sarcomere
Archives of Biochemistry and Biophysics
Talks, contributed
K. J. McCabe, Y. Aboelkassem, A. Teitgen, M. Regnier and A. D. McCulloch
Multiscale modelling determines mechanisms of action for 2'-deoxy-ATP, a myosin activating therapeutic for heart failure
VPH 2020, Paris, France (Virtual)
2019
Journal Articles
Y. Aboelkassem, K. J. McCabe, G. Huber, M. Regnier, A. J. McCammon and A. D. McCulloch
A Stochastic Multiscale Model of Cardiac Thin Filament Activation Using Brownian-Langevin Dynamics
Biophysical Journal
V. Timmermann, A. G. Edwards, S. Wall, J. Sundnes and A. D. McCulloch
Arrhythmogenic current generation by myofilament-triggered Ca2+ release and sarcomere heterogeneity
Biophysical Journal
J. D. Powers, C. Yuan, K. J. McCabe, J. D. Murray, M. C. Childers, G. Flint, F. Moussavi-Harami, S. Mohran, R. Castillo, C. Zuzek, W. Ma, V. Daggett, A. D. McCulloch, T. C. Irving and M. Regnier
Cardiac myosin activation with 2-deoxy-ATP via increased electrostatic interactions with actin
Proceedings of the National Academy of Sciences
Y. Aboelkassem, J. D. Powers, K. J. McCabe and A. D. McCulloch
Multiscale Models of Cardiac Muscle Biophysics and Tissue Remodeling in Hypertrophic Cardiomyopathies
Current Opinion in Biomedical Engineering
K. H. Jæger, A. G. Edwards, A. D. McCulloch and A. Tveito
Properties of cardiac conduction in a cell-based computational model
PLoS Computational Biology
G. Balaban, B. P. Halliday, W. Bai, B. Porter, C. Malvuccio, P. Lamata, C. A. Rinaldi, G. Plank, D. Rueckert, S. K. Prasad and M. J. Bishop
Scar shape analysis and simulated electrical instabilities in a non-ischemic dilated cardiomyopathy patient cohort
PLOS Computational Biology
Proceedings, refereed
V. Timmermann, K. Vincent, J. Sundnes and A. D. McCulloch
Mechano-electric feedback and arrhythmogenic current generation in a computational model of coupled myocytes
ICBME2019--YC Fung 100th Birthday Conference
Talks, contributed
V. Timmermann, J. Sundnes, S. Wall, A. D. McCulloch and A. G. Edwards
A one-dimensional computational study of mechano-electric feedback and arrhythmogenic current generation
Gordon Research Conference "Cardiac Arrhythmia Mechanisms", Barga, Italy
Y. Aboelkassem, A. K. Diem, K. Valen-Sendstad and A. D. McCulloch
Autonomic Modelling of Interaction between Coronary Perfusion Flow and Myocardium Mechanics using Computational Poroelasticity
International Society of Autonomic Neuroscience, Los Angeles, CA, USA
V. Timmermann, A. T. Quinn and A. D. McCulloch
Mechano-Electric Coupling and Arrhythmogenic Current Generation in a Computational Model of Coupled Myocytes
Cardiac Physiome, Maastricht, Netherlands
2018
Posters
K. J. McCabe, Y. Aboelkassem, S. Dewan, M. Regnier and A. D. McCulloch
A Markov State Model of the Sarcomere to Explain the Effects of dATP on Cardiac Contraction
Y. Aboelkassem, K. J. McCabe, G. Huber, J. Sundnes and A. D. McCulloch
Turning the Azimuthal Motions of Adjacent Tropomyosins into a Coupled N-body Problem in a Brownian Model of Cardiac Thin Filament Activation
Biophysical Journal
Talks, contributed
V. Timmermann, J. Sundnes, S. Wall, A. D. McCulloch and A. G. Edwards
A computational study of the contribution of mechano-electric feedback to arrhythmogenic current generation
Berlin, Germany
2017
Journal Articles
V. Timmermann, L. A. Dejgaard, K. H. Haugaa, A. G. Edwards, J. Sundnes, A. D. McCulloch and S. Wall
An integrative appraisal of mechano-electric feedback mechanisms in the heart
Progress in biophysics and molecular biology
S. Dewan, K. J. McCabe, M. Regnier and A. D. McCulloch
Insights and Challenges of Multi-Scale Modeling of Sarcomere Mechanics in cTn and Tm DCM Mutants—Genotype to Cellular Phenotype
Frontiers in Physiology
Posters
V. Timmermann, L. A. Dejgaard, A. D. McCulloch, K. H. Haugaa, A. G. Edwards and S. Wall
Role of Electromechanical Feedback in Stretch Induced Arrhythmias : From Single Myocyte to Multicellular Level
Talks, contributed
V. Timmermann, A. G. Edwards, J. Sundnes, A. D. McCulloch, S. Wall and T. A. Quinn
Integrated Mechanisms of Mechano-Electric feedback in Ischemic Arrhythmogenesis
Bergen, Norway
2016
Journal Articles
S. Morotti, A. D. McCulloch, D. M. Bers, A. G. Edwards and E. Grandi
Atrial-selective targeting of arrhythmogenic phase-3 early afterdepolarizations in human myocytes
Journal of Molecular and Cellular Cardiology
B. Leon, V. Naumova, E. Ruiz-Velazquez, A. D. McCulloch and E. Sanchez
Combination of Neural Inverse Optimal Control with a Kernel-Based Regularization Learning Algorithm to Prevent Hypoglycemia in Type 1 Diabetes Patients
IEEE Transactions on Neural Networks and Learning Systems
A. Tveito, G. T. Lines, A. G. Edwards and A. D. McCulloch
Computing rates of Markov models of voltage-gated ion channels by inverting partial differential equations governing the probability density functions of the conducting and non-conducting states
Mathematical Biosciences
S. Dewan, K. J. McCabe, M. Regnier, A. D. McCulloch and S. Lindert
Molecular Effects of cTnC DCM Mutations on Calcium Sensitivity and Myofilament Activation—An Integrated Multiscale Modeling Study
The Journal of Physical Chemistry B
Book Chapters
A. G. Edwards, J. E. Hake, A. P. Michailova, M. Hoshijima and A. D. McCulloch
Calcium Signaling in Cardiomyocyte Models With Realistic Geometries (7th Edition)
Cardiac Electrophysiology: From Cell to Bedside
Posters
V. Timmermann, A. G. Edwards, J. Sundnes, A. D. McCulloch and S. Wall
Role of Electromechanical Feedback in Mitral Valve Prolapse Arrhythmia
2015
Journal Articles
S. Morotti, A. D. McCulloch, D. M. Bers, A. G. Edwards and E. Grandi
Atrial-selective targeting of arrhythmogenic phase-3 early afterdepolarizations in human myocytes
Journal of Molecular and Cellular Cardiology
K. P. Vincent, M. J. Gonzales, A. K. Gillette, C. T. Villongco, S. Pezzuto, J. H. Omens, M. J. Holst and A. D. McCulloch
High-order finite element methods for cardiac monodomain simulations
Frontiers in Physiology
B. L. de Oliveira, J. Sundnes, S. Wall and A. D. McCulloch
Increased Membrane Capacitance Is the Dominant Mechanism of Stretch-Dependent Conduction Slowing in the Rabbit Heart: a Computational Study
Cellular and Molecular Bioengineering
Posters
S. Morotti, A. D. McCulloch, D. M. Bers, A. G. Edwards and E. Grandi
Ranolazine Prevents Phase-3 Early Afterdepolarizations in Human Atrial Myocytes by Inhibiting Na Current Non-Equilibrium Reactivation
Biophysical Society annual meeting
2014
Journal Articles
S. Morotti, A. G. Edwards, A. D. McCulloch, D. M. Bers and E. Grandi
A novel computational model of mouse myocyte electrophysiology to assess the synergy between Na+ loading and CaMKII
The Journal of physiology
S. Morotti, A. G. Edwards, A. D. McCulloch, D. M. Bers and E. Grandi
A novel computational model of mouse myocyte electrophysiology to assess the synergy between Na+ loading and CaMKII
The Journal of Physiology
E. Pfeiffer, J. Tangney, J. Omens and A. D. McCulloch
Biomechanics of Cardiac Electromechanical Coupling and Mechanoelectric Feedback.
Journal of Biomechanical Engineering
E. Pfeiffer, A. Wright, A. G. Edwards, J. Stowe, K. McNall, J. Tan, I. Niesman, H. Patel, D. Roth, J. Omens and A. D. McCulloch
Caveolae in ventricular myocytes are required for stretch-dependent conduction slowing
Journal of Molecular and Cellular Cardiology
J. E. Hake, P. M. Kekenes-Huskey and A. D. McCulloch
Computational modeling of subcellular transport and signaling
Current Opinion in Structural Biology
J. Sundnes, S. Wall, H. Osnes, T. Thorvaldsen and A. D. McCulloch
Improved Discretisation and Linearisation of Active Tension in Strongly Coupled Cardiac Electro-Mechanics Simulations
Computer Methods in Biomechanics and Biomedical Engineering
A. G. Edwards, E. Grandi, J. E. Hake, S. Patel, P. Li, S. Miyamoto, J. H. Omens, J. H. Brown, D. M. Bers and A. D. McCulloch
Non-equilibrium reactivation of Na+ current drives early afterdepolarizations in mouse ventricle
Circulation: Arrhythmia and Electrophysiology
K. P. Vincent, A. D. McCulloch and A. G. Edwards
Toward a hierarchy of mechanisms in CaMKII-mediated arrhythmia
Frontiers in Pharmacology
K. P. Vincent, A. D. McCulloch and A. G. Edwards
Toward a hierarchy of mechanisms in CaMKII-mediated arrhythmia
Frontiers in Pharmacology
Proceedings, non-refereed
P. M. Kekenes-Huskey, A. G. Edwards, J. E. Hake, A. P. Michailova, A. J. McCammon and A. D. McCulloch
A Markov-State Model for the Regulation of the Sarcoplasmic Reticulum Ca2+ ATPase by Phospholamban
Annual meeting in Biophysical society
Talks, keynote
A. D. McCulloch
Multi-Scale Modeling of the Failing Heart:
From Mouse to Man
Simula-UiO-UCSD Summer School in Cardiac Modeling
2013
Journal Articles
M. J. Gonzales, G. Sturgeon, A. Krishnamurthy, J. E. Hake, R. Jonas, P. Stark, W. Rappel, S. M. Narayan, Y. Zhang, W. P. Segars and A. D. McCulloch
A Three-Dimensional Finite Element Model of Human Atrial Anatomy: New Methods for Cubic Hermite Meshes With Extraordinary Vertices
Medical Image Analysis
P. M. Kekenes-Huskey, T. Liao, A. K. Gillette, J. E. Hake, Y. Zhang, A. P. Michailova, A. D. McCulloch and A. J. McCammon
Molecular and Subcellular-Scale Modeling of Nucleotide Diffusion in the Cardiac Myofilament Lattice
Biophysical Journal
A. Krishnamurthy, C. T. Villongco, J. Chuang, L. R. Frank, V. Nigam, E. Belezzuoli, P. Stark, D. E. Krummen, S. Narayan, J. H. Omens and A. D. McCulloch
Patient-Specific Models of Cardiac Biomechanics
Journal of Computational Physics
D. Westenbrink, A. G. Edwards, A. D. McCulloch and J. H. Brown
The promise of CaMKII inhibition for heart disease: preventing heart failure and arrhythmias
Expert opinion on therapeutic targets
Book Chapters
A. P. Michailova, A. G. Edwards, J. E. Hake, M. Hoshijima and A. D. McCulloch
Calcium Signaling in Cardiomyocyte Models With Realistic Geometries (6th Edition)
Cardiac Electrophysiology: From Cell to Bedside
2012
Journal Articles
J. E. Hake, A. G. Edwards, Z. Yu, P. M. Kekenes-Huskey, A. P. Michailova, A. J. McCammon, M. J. Holst, M. Hoshijima and A. D. McCulloch
Modeling Cardiac Calcium Sparks in a Three-Dimensional Reconstruction of a Calcium Release Unit
The Journal of Physiology
P. M. Kekenes-Huskey, Y. Cheng, J. E. Hake, F. B. Sachse, J. H. Bridge, M. J. Holst, A. J. McCammon, A. D. McCulloch and A. P. Michailova
Modeling Effects of L-Type Ca2+ Current and Na+-Ca2+ Exchanger on Ca2+ Trigger Flux in Rabbit Myocytes With Realistic T-Tubule Geometries
Frontiers in Physiology
A. Tveito, G. T. Lines, A. G. Edwards, M. Maleckar, A. P. Michailova, J. E. Hake and A. D. McCulloch
Slow Calcium-Depolarization-Calcium Waves May Initiate Fast Local Depolarization Waves in Ventricular Tissue
Progress in Biophysics and Molecular Biology
Posters
P. M. Kekenes-Huskey, J. E. Hake, Y. Cheng, M. J. Holst, F. B. Sachse, J. H. Bridge, A. D. McCulloch, A. J. McCammon and A. P. Michailova
Modeling Calcium Dynamics in Realistic Rabbit Ventricular Myocytes With Several Transverse Tubules
J. E. Hake, A. G. Edwards, Z. Yu, P. M. Kekenes-Huskey, A. P. Michailova, A. J. McCammon, M. J. Holst, M. Hoshijima and A. D. McCulloch
Modeling Calcium Sparks in a Three-Dimensional Reconstruction of a Cardiac Calcium Release Unit
A. G. Edwards, J. E. Hake, J. H. Brown and A. D. McCulloch
βAR-Stimulation Causes EADs But Not DADs in Pre-Failure CAMKIIδC Transgenic Myocytes
Biophysical Society annual meeting
2011
Journal Articles
E. J. Howard, J. W. Covell, L. J. Mulligan, A. D. McCulloch and J. H. Omens
Improvement in Pump Function With Endocardial Biventricular Pacing Increases With Activation Time at the Left Ventricular Pacing Site in Failing Canine Hearts
American Journal of Physiology - Heart and Circulatory Physiology
S. G. Campbell and A. D. McCulloch
Multi-Scale Computational Models of Familial Hypertrophic Cardiomyopathy: Genotype to Phenotype
Journal of the Royal Society Interface
A. Tveito, G. T. Lines, P. Li and A. D. McCulloch
On Defining Candidate Drug Characteristics for Long-QT
Mathematical Biosciences and Engineering
Posters
J. E. Hake, W. E. Louch, K. Haugen, I. Sjaastad, O. M. Sejersted, A. D. McCulloch, A. P. Michailova and G. T. Lines
A Stochastic Model of the Ryanodine Receptor Featuring Coupled Gating and Competitive Binding of Luminal and Cytosolic Ca2+ and Mg2+
2010
Journal Articles
J. G. Jacot, H. Kita-Matsuo, K. A. Wei, H. S. V. Chen, J. H. Omens, M. Mercola and A. D. McCulloch
Cardiac Myocyte Force Development During Differentiation and Maturation
Annals of the New York Academy of Sciences
S. G. Campbell, F. V. Lionetti, K. S. Campbell and A. D. McCulloch
Coupling of Adjacent Tropomyosins Enhances Cross-Bridge-Mediated Cooperative Activation in a Markov Model of the Cardiac Thin Filament
Biophysical Journal
n. null, A. Zemljic-Harpf, R. S. Ross, L. R. Frank, A. D. McCulloch and J. H. Omens
Determination of Three-Dimensional Ventricular Strain Distributions in Gene-Targeted Mice Using Tagged MRI
Magnetic Resonance in Medicine
Y. Cheng, Z. Yu, M. Hoshijima, M. J. Holst, A. D. McCulloch, A. J. McCammon and A. P. Michailova
Numerical Analysis of Ca2+ Signaling in Rat Ventricular Myocytes With Realistic Transverse-Axial Tubular Geometry and Inhibited Sarcoplasmic Reticulum
PLoS Computational Biology
J. D. Feala, J. Cortes, P. M. Duxbury, C. Piermarocchi, A. D. McCulloch and G. Paternostro
Systems Approaches and Algorithms for Discovery of Combinatorial Therapies
Wiley Interdisciplinary Reviews: Systems Biology and Medicine
J. H. Omens, A. D. McCulloch and L. J. Mulligan
Ventricular Dilation and Electrical Dyssynchrony Synergistically Increase Regional Mechanical Non-Uniformity But Not Mechanical Dyssynchrony: a Computational Model
Circulation: Heart Failure
J. H. Omens, A. D. McCulloch and L. J. Mulligan
Ventricular Dilation and Electrical Dyssynchrony Synergistically Increase Regional Mechanical Non-Uniformity But Not Mechanical Dyssynchrony; a Computational Model
Circulation: Heart Failure
Proceedings, refereed
F. V. Lionetti, A. D. McCulloch and S. Baden
GPU Accelerated Cardiac Electrophysiology
Proceedings of the International Conference on Applied Parallel Computing
F. V. Lionetti, A. D. McCulloch and S. Baden
Source-to-Source Optimization of CUDA C for GPU Accelerated Cardiac Cell Modeling
Proceedings of Euro-Par 2010
Book Chapters
J. Aguado-Sierra, F. V. Lionetti, D. Hunt, C. T. Villongco, M. Gonzales, S. G. Campbell and A. D. McCulloch
A Computational Framework for Patient-Specific Multi-Scale Cardiac Modeling
Patient-Specific Modeling of the Cardiovascular System; Technology-Driven Personalized Medicine
2009
Journal Articles
S. G. Campbell, E. Howard, J. Aguado-Sierra, B. A. Coppola, J. H. Omens, L. J. Mulligan and A. D. McCulloch
Effect of Transmurally Heterogeneous Myocyte Excitation-contraction Coupling on Canine Left Ventricular Electromechanics
Experimental Physiology
A. M. Raskin, M. Hoshijima, E. Swanson, A. D. McCulloch and J. H. Omens
Hypertrophic Gene Expression Induced by Chronic Stretch of Excised Mouse Heart Muscle
Mol Cell Biomech.
J. D. Feala, L. C. Coquin, D. Zhou, G. G. Haddad, G. Paternostro and A. D. McCulloch
Metabolism As Means for Hypoxia Adaptation: Metabolic Profiling and Flux Balance Analysis
BMC Systems Biology
J. D. Feala, J. Cortes, P. M. Duxbury, C. Piermarocchi, A. D. McCulloch and G. Paternostro
Systems Approaches and Algorithms for Discovery of Combinatorial Therapies
Systems Biology and Medicine
Proceedings, non-refereed
F. V. Lionetti, A. D. McCulloch and S. Baden
GPU Accelerated Electrophysiology Simulations
Proceedings of the 2009 ACM/IEEE Conference on supercomputing (SC 2009)
F. V. Lionetti, A. D. McCulloch and S. Baden
GPU Accelerated Solvers for ODEs Describing Cardiac Membrane Equations
Proceeding of the GPU technology Conference
Talks, contributed
F. V. Lionetti, A. D. McCulloch and S. Baden
GPU Accelerated Electrophysiology Simulations
Talk, poster at the 2009 ACM/IEEE Conference on Supercomputing (SC 2009)
F. V. Lionetti, A. D. McCulloch and S. Baden
GPU Accelerated Electrophysiology Simulations.
Talk, Poster at GPU Technology conference, San Jose, California
2008
Journal Articles
C. L. Cai, J. Martin, Y. Sun, L. Cui, L. Wang, K. Ouyang, L. Yang, L. Bu, X. Liang, X. Zhang, W. B. Stallcup, C. P. Denton, A. D. McCulloch, J. Chen and S. M. Evans
A Myocardial Lineage Derives From Tbx18 Epicardial Cells
Nature
J. Lumens, K. Vernooy, J. H. Omens, L. J. Mulligan, T. Delhaas, T. Arts, A. D. McCulloch and F. W. Prinzen
Cardiac Resynchronization: Insight From Experimental and Computational Models
Progress in Biophysics and Molecular Biology
J. D. Feala, J. H. Omens, G. Paternostro and A. D. McCulloch
Discovering Regulators of the Drosophila Cardiac Hypoxia Response Using Automated Phenotyping Technology
Annals of the New York Academy of Sciences
S. G. Campbell, S. N. Flaim, C. H. Leem and A. D. McCulloch
Mechanisms of Transmurally Varying Myocyte Electromechanics in an Integrated Computational Model
Philosophical Transactions of the Royal Society A
J. J. Jacot, A. D. McCulloch and J. H. Omens
Substrate Stiffness Affects the Functional Maturation of Neonatal Rat Ventricular Myocytes
Biophysiology Journal
W. Li, V. Gurev and A. D. McCulloch
The Role of Mechanoelectric Feedback in Vulnerability to Electric Shock
Progress in Biophysics and Molecular Biology
Talks, contributed
A. D. McCulloch
Emerging Role for Multi-Scale Modeling in the Biomechanical Device Industry
Keynote talk at the 3rd ASME Frontiers in Biomechanical Devices Conference, Irvine, California, USA
A. D. McCulloch
Mechanobiology of Normal and Failing Myocardium
Talk at the Physiology Department, Oxford University
A. D. McCulloch
Mechanosensing and Mechanotransduction in the Myocardium
Seminar at the Cardiology Department, Academic Hospital Maastricht, The Netherlands
A. D. McCulloch
Multi-Scale Modeling and Systems Biology of Cardiac Regulatory Mechanisms
Invited talk at the MEI International Symposium Physiome and Systems Biology for Integrated Life Sciences and Predictive Medicine, San Fransisco
A. D. McCulloch
Multi-Scale Modeling of Cardiac Electromechanics
Talk at the Biomechanical Engineering Math Seminar, Worchester Polytechnic Institute
A. D. McCulloch
Multi-Scale Modeling of Cardiac Electromechanics
Talk at the Symposium on Computational Physiology, Experimental Biology 2008, San Diego
A. D. McCulloch
Multi-Scale Modeling of Cardiac Mechanoenergetics
Talk at the Welcome Trust Physiome Workshop on Multi-scale Modeling of the heart, Auckland, New Zealand
A. D. McCulloch
Multi-Scale Modeling of Ventricular Electromechanics
Invited talk at the Cardiovascular System Dynamics Society HVIII Conference, St. Louis, USA
A. D. McCulloch
Multi-Scale Modeling of the Heart
Invited talk at the NCRR P41 Directors, National Library of Medicine, NIH, Bethesda, Maryland, USA
A. D. McCulloch
Physiome Research in the USA
Invited talk at ICT-BIO, The European Commission, Brussels
A. D. McCulloch
Seminar: Multi-Scale Modeling of the Heart
Talk at the MURPA eSeminar, Monash University, Melbourne, Australia
A. D. McCulloch
Systems Biology and Multi-Scale Modeling of the Heart
Seminar at the University of Washington, Department of Bioengineering
A. D. McCulloch
Systems Biology and Multi-Scale Modeling of the Heart
Plenary lecture at Pacific Biocomputing Symposium, Kona, Hawaii
A. D. McCulloch
Systems Biology and Multi-Scale Modeling of the Heart
Talk at University of Illinois, Chicago, Department of Physiology and Biophysics
A. D. McCulloch
Towards Image-Based Patient-Specific Multi-Scale Modeling of the Failing Heart
Invited talk at the 2008 SIAM Life Sciences Conferences, Session MS35, Montreal, Canada
2007
Journal Articles
S. N. Flaim, W. R. Giles and A. D. McCulloch
Arrhythmogenic Consequences of Na+ Channel Mutations in the Transmurally Heterogeneous Mammalian Left Ventricle: Analysis of the I1768V SCN5A Mutation
Heart Rhythm
M. L. Neal, J. B. Bassingthwaighte, J. H. Omens and A. D. McCulloch
Coupling of a 3D Finite Element Model of Cardiac Ventricular Mechanics to Lumped Systems Models of the Systemic and Pulmonic Circulation
Ann. Biomed. Eng.
J. D. Feala, L. C. Coquin, A. D. McCulloch and G. Paternostro
Flexibility in Energy Metabolism Supports Hypoxia Tolerance in Drosophila Flight Muscle: Metabolomic and Computational Systems Analysis
Mol Syst Biol.
C. M. Ingrassia, T. P. Usyk, A. D. McCulloch, K. D. Costa and J. W. Holmes
Model-Based Development of Four-Dimensional Wall Motion Measures
Computer Methods in Applied Mechanics and Engineering
A. P. Michailova, W. Lorentz and A. D. McCulloch
Modeling Transmural Heterogeneity of KATP Current in Rabbit Ventricular Myocytes
American Journal of Physiology - Cell Physiology
K. E. Broderick, M. Balasubramanian, A. Chan, P. Potluri, J. Feala, D. Belke, A. D. McCulloch, V. S. Sharma, R. B. Pilz, T. D. Bigby and G. R. Boss
The Cobalamin Precursor Cobinamide Detoxifies Nitroprusside-Generated Cyanide
Experimental Biology and Medicine
Talks, contributed
A. D. McCulloch
Multi-Scale Modeling of Cardiac Electromechanical Interactions
Talk at CBC Workshop on Biomedical Computing, Simula
2006
Journal Articles
P. J. Hunter, W. Li, A. D. McCulloch and D. Noble
Multiscale Modeling: Physiome Project Standards, Tools, and Databases
IEEE Computer Magazine
J. H. Omens and A. D. McCulloch
Myocyte Shearing, Myocardial Sheets, and Microtubules
Circulation Research
P. N. Costandi, L. R. Frank, A. D. McCulloch and J. H. Omens
Role of Diastolic Properties in the Transition to Failure in a Mouse Model of Cardiac Dilatation
American Journal of Physiology - Heart and Circulatory Physiology