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Arrhythmogenic influence of mutations in a myocyte‑based computational model of the pulmonary vein sleeve." Nature Scientific Reports 12 (2022): 7040.
"Image-Driven Modeling of Nanoscopic Cardiac Function: Where Have We Come From, and Where Are We Going?" Frontiers in Physiology 13 (2022).
louch_et_al-2022-frontiers_in_physiology.pdf (4.25 MB)
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Mechanisms of spontaneous Ca 2+ release‐mediated arrhythmia in a novel 3D human atrial myocyte model: I. Transverse‐axial tubule variation." The Journal of Physiology (2022).
"Mechanisms of spontaneous Ca2+ release‐mediated arrhythmia in a novel 3D human atrial myocyte model: II Ca2+‐handling protein variation." The Journal of Physiology 116 (2022).
"Metabolically driven maturation of human-induced-pluripotent-stem-cell-derived cardiac microtissues on microfluidic chips." Nature Biomedical Engineering 6, no. 4 (2022): 372-388.
"Prolonged β-adrenergic stimulation disperses ryanodine receptor clusters in cardiomyocytes." eLife 11 (2022).
"Validating the Arrhythmogenic Potential of High-, Intermediate-, and Low-Risk Drugs in a Human-Induced Pluripotent Stem Cell-Derived Cardiac Microphysiological System." ACS Pharmacology & Translational Science 5, no. 8 (2022): 652-667.
"Calcium Signaling in Cardiomyocyte Models With Realistic Geometries." In Zipes and Jalife's Cardiac Electrophysiology: From Cell to Bedside, edited by J. Jalife and W. G. Stevenson, 362-375. 8th ed. Vol. 1. Elsevier, 2021.
"A computational method for identifying an optimal combination of existing drugs to repair the action potentials of SQT1 ventricular myocytes." PLoS Computational Biology 17 (2021): e1009233.
"From Millimeters to Micrometers; Re-introducing Myocytes in Models of Cardiac Electrophysiology." Frontiers in Physiology 12 (2021): 763584.
"Heart Muscle Microphysiological System for Cardiac Liability Prediction of Repurposed COVID-19 Therapeutics." Frontiers in Pharmacology 12 (2021): 684252.
"In vitro safety “clinical trial” of the cardiac liability of drug polytherapy." Clinical and Translational Science 14, no. 3 (2021): 1155-1165.
"Sarcoplasmic Reticulum Calcium Release Is Required for Arrhythmogenesis in the MouseData_Sheet_1.pdf." Frontiers in Physiology 129247113307196118101757330290951073619410426311810310255549995881112965921565931388107972921061031069987209102119109419102782 (2021).
"Sex‐Specific Classification of Drug‐Induced Torsade de Pointes Susceptibility Using Cardiac Simulations and Machine Learning." Clinical Pharmacology & Therapeutics 1105970708108167, no. 2 (2021): 380-391.
"3D Dstorm Imaging Reveals Camkii-Dependent Dispersal of Ryanodine Receptor Clusters in Failing Rat Cardiomyocytes In Biophysical Journal. Biophysical Journal: Cell Press, 2020.
A computational study on integrated mechanisms of mechano-electric feedback in ischemic arrhythmogenesis." SAGE (2020).
"In Vitro Safety “Clinical Trial” of the Cardiac Liability of Hydroxychloroquine and Azithromycin as COVID19 Polytherapy." Clinical Pharmacology & Therapeutics (2020).
"A unified computational model for cortical post-synaptic plasticity." eLife 9 (2020).
"3D dSTORM imaging reveals novel detail of ryanodine receptor localization in rat cardiac myocytes." The Journal of Physiology 597, no. 2 (2019): 399-418.
"Arrhythmogenic current generation by myofilament-triggered Ca2+ release and sarcomere heterogeneity." Biophysical Journal 117, no. 12 (2019): 2471-2485.
"Biophysical Psychiatry—How Computational Neuroscience Can Help to Understand the Complex Mechanisms of Mental Disorders." Frontiers in psychiatry 10 (2019).
revscz.pdf (1.2 MB)
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A one-dimensional computational study of mechano-electric feedback and arrhythmogenic current generation In Gordon Research Conference "Cardiac Arrhythmia Mechanisms", Barga, Italy., 2019.
Properties of cardiac conduction in a cell-based computational model." PLoS Computational Biology 15, no. 5 (2019).
"Alterations in Schizophrenia-Associated Genes Can Lead to Increased Power in Delta Oscillations." Cerebral Cortex 29 (2018): 875-891.
scznet_withfigs.pdf (5.14 MB)
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Computational Modeling of Electrophysiology and Pharmacotherapy of Atrial Fibrillation: Recent Advances and Future Challenges." Frontiers in Physiology 9 (2018): 1221.
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