Publications | Simula

2019

K. H. Jæger, S. Wall and A. Tveito. "Detecting undetectables: Can conductances of action potential models be changed without appreciable change in the transmembrane potential?" Chaos 29 (2019).

A. P. Buccino, M. Kuchta, K. H. Jæger, T. V. Ness, P. Berthet, K. Mardal, G. Cauwenberghs and A. Tveito. "How does the presence of neural probes affect extracellular potentials?" Journal of Neural Engineering 16 (2019): 026030.

K. H. Jæger, A. G. Edwards, A. D. McCulloch and A. Tveito. "Properties of cardiac conduction in a cell-based computational model." PLoS Computational Biology 15, no. 5 (2019).

2018

A. Tveito, M. M. Maleckar and G. T. Lines. "Computing Optimal Properties of Drugs Using Mathematical Models of Single Channel Dynamics." Computational and Mathematical Biophysics 6, no. 1 (2018): 41-64.

computing_optimal_properties_of_drugs_using_mathematical_models_of_single_channel_dynamics.pdf (1.45 MB)

S. Wall, K. H. Jæger, N. Huebsch, B. Charrez, K. Healy and A. Tveito. In Silico - Augmented Cardiac Microphysiological Systems for Evaluating Cardiac Drug Effects. Keystone Organ on Chip Symposium, Montana, USA, 2018.

S. Wall, K. H. Jæger, N. Huebsch, B. Charrez, K. Healy and A. Tveito. In Silico - Augmented Cardiac Microphysiological Systems for Evaluating Cardiac Drug Effects. BMES Conference, Atlanta, USA, 2018.

S. Wall, A. Tveito, K. H. Jæger, A. Edwards, K. Healy, N. Huebsch and B. Charrez. In Silico Modeling of Cardiac Microphysiological Systems for Evaluating Drug Side Effects In Heart By Numbers Conference, Berlin, Germany., 2018.

A. Tveito, K. H. Jæger, N. Huebsch, B. Charrez, A. G. Edwards, S. Wall and K. E. Healy. "Inversion and computational maturation of drug response using human stem cell derived cardiomyocytes in microphysiological systems." Nature Scientific Reports 8 (2018).

2017

A. Tveito, K. H. Jæger, M. Kuchta, K. Mardal and M. E. Rognes. "A cell-based framework for numerical modelling of electrical conduction in cardiac tissue." Frontiers in Physics, Computational Physics 5 (2017).

A. Tveito, K. H. Jæger, G. T. Lines, Ł. Paszkowski, J. Sundnes, A. G. Edwards, T. Mäki-Marttunen, G. Halnes and G. T. Einevoll. "An Evaluation of the Accuracy of Classical Models for Computing the Membrane Potential and Extracellular Potential for Neurons." Frontiers in Computational Neuroscience 11 (2017): 27.

T. Mäki-Marttunen, G. T. Lines, A. G. Edwards, A. Tveito, A. M. Dale, G. T. Einevoll and O. A. Andreassen. "Pleiotropic effects of schizophrenia-associated genetic variants in neuron firing and cardiac pacemaking revealed by computational modeling." Translational Psychiatry 7 (2017): 5.

2016

A. Tveito and G. T. Lines. Computing characterizations of drugs for ion channels and receptors using Markov models. Vol. LNCSE Vol. 111. Heidelberg, Germany: Springer, 2016.

A. Tveito, G. T. Lines, A. G. Edwards and A. D. McCulloch. "Computing rates of Markov models of voltage-gated ion channels by inverting partial differential equations governing the probability density functions of the conducting and non-conducting states." Mathematical Biosciences 277 (2016): 126-135.

2015

A. Tveito, H. P. Langtangen and R. Winther. "Computational Partial Differential Equations." In Encyclopedia of Applied and Computational Mathematics, edited by B. Engquist, 271-278. Vol. 1. Berlin, Heidelberg: Springer-Verlag, 2015.

Encyclopedia of Applied and Computational Mathematics, Edited by B. Engquist, M. Alber, E. Hairer, J. Håstad, A. Iserles, H. P. Langtangen, C. Le Bris, C. Lubich, A. J. Majda, J. R. McLaughlin et al. Vol. 1. Berlin, Heidelberg: Springer-Verlag, 2015.

Encyclopedia of Applied and Computational Mathematics, Edited by B. Engquist, M. Alber, E. Hairer, J. Håstad, A. Iserles, H. P. Langtangen, C. Le Bris, C. Lubich, A. J. Majda, J. R. McLaughlin et al. Vol. 2. Berlin / Heidelberg: Springer-Verlag, 2015.

J. Sundnes, S. Wall, V. Timmermann and A. Tveito. Mechano-electric feedback as a source of ectopic activity In Gordon Research Conference on Arrhythmia Mechanisms, Lucca, Italy. Gordon Research Conference on Arrhythmia Mechanisms, Lucca, Italy, 2015.

H. P. Langtangen, U. Rüde and A. Tveito. "Scientific Computing." In Encyclopedia of Applied and Computational Mathematics, edited by B. Engquist, 1302-1310. Vol. 2. Berlin, Heidelberg: Springer-Verlag, 2015.

2013

A. M. Bruaset and A. Tveito. Conversations About Challenges in Computing. Springer, 2013.

Simula.simula.2060.pdf (254.8 KB)

P. Li, G. T. Lines, M. Maleckar and A. Tveito. "Mathematical Models of Cardiac Pacemaking Function." Frontiers in Physics 1 (2013).

Simula.simula.2274.pdf (4.37 MB)

2012

A. Tveito, G. T. Lines, M. E. Rognes and M. Maleckar. "An Analysis of the Shock Strength Needed to Achieve Defibrillation in a Simplified Mathematical Model of Cardiac Tissue." International Journal of Numerical Analysis and Modeling 9 (2012): 644-657.

Simula.simula.542.pdf (318.37 KB)

A. Tveito, G. T. Lines, J. E. Hake and A. G. Edwards. "Instabilities of the Resting State in a Mathematical Model of Calcium Handling in Cardiac Myocytes." Mathematical Biosciences 236 (2012): 97-107.

A. Tveito, G. T. Lines and M. Maleckar. "A Note on a Possible Pro-Arrhythmic Property of Anti-Arrhythmic Drugs Aimed at Improving Gap-Junction Coupling." Biophysical Journal 102 (2012): 231-237.