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2022
K. H. Jæger, A. G. Edwards, W. R. Giles and A. Tveito. "Arrhythmogenic influence of mutations in a myocyte‑based computational model of the pulmonary vein sleeve." Nature Scientific Reports 12 (2022): 7040.
K. H. Jæger and A. Tveito. "Deriving the Bidomain Model of Cardiac Electrophysiology From a Cell-Based Model; Properties and Comparisons." Frontiers in Physiology 12 (2022): 811029.
N. Huebsch, B. Charrez, G. Neiman, B. Siemons, S. C. Boggess, S. Wall, V. Charwat, K. H. Jæger, D. Cleres, Å. Telle et al. "Metabolically driven maturation of human-induced-pluripotent-stem-cell-derived cardiac microtissues on microfluidic chips." Nature Biomedical Engineering 6, no. 4 (2022): 372-388.
V. Charwat, B. Charrez, B. A. Siemons, H. Finsberg, K. H. Jæger, A. G. Edwards, N. Huebsch, S. Wall, E. Miller, A. Tveito et al. "Validating the Arrhythmogenic Potential of High-, Intermediate-, and Low-Risk Drugs in a Human-Induced Pluripotent Stem Cell-Derived Cardiac Microphysiological System." ACS Pharmacology & Translational Science 5, no. 8 (2022): 652-667.
2021
A. J. Ellingsrud, C. Daversin-Catty and M. E. Rognes. "A cell-based model for ionic electrodiffusion in excitable tissue." In Modeling Excitable Tissue: The EMI Framework, edited by K. Mardal, M. E. Rognes and A. Tveito, 14-27. Cham: Springer International Publishing, 2021.
K. H. Jæger, A. G. Edwards, W. R. Giles and A. Tveito. "A computational method for identifying an optimal combination of existing drugs to repair the action potentials of SQT1 ventricular myocytes." PLoS Computational Biology 17 (2021): e1009233.
K. H. Jæger, S. Wall and A. Tveito. "Computational prediction of drug response in short QT syndrome type 1 based on measurements of compound effect in stem cell-derived cardiomyocytes." PLoS Computational Biology 17, no. 2 (2021): e1008089.
K. H. Jæger and A. Tveito. "Derivation of a Cell-Based Mathematical Model of Excitable Cells." In Modeling Excitable Tissue: The EMI Framework, edited by A. Tveito, K. Mardal and M. E. Rognes, 1-13. Vol. 7. Cham: Springer International Publishing, 2021.
K. H. Jæger and A. Tveito. "Derivation of a Cell-Based Mathematical Model of Excitable Cells." In Modeling Excitable Tissue: The EMI Framework, edited by A. Tveito, K. Mardal and M. E. Rognes, 1-13. Vol. 7. Cham: Springer International Publishing, 2021.
K. H. Jæger, K. G. Hustad, X. Cai and A. Tveito. "Efficient numerical solution of the EMI model representing the extracellular space (E), cell membrane (M) and intracellular space (I) of a collection of cardiac cells." Frontiers in Physics 8 (2021): 579461.
K. H. Jæger, A. G. Edwards, W. R. Giles and A. Tveito. "From Millimeters to Micrometers; Re-introducing Myocytes in Models of Cardiac Electrophysiology." Frontiers in Physiology 12 (2021): 763584.
K. H. Jæger, V. Charwat, S. Wall, K. E. Healy and A. Tveito. "Identifying drug response by combining measurements of the membrane potential, the cytosolic calcium concentration, and the extracellular potential in microphysiological systems." Frontiers in Pharmacology 11 (2021): 569489.
Å. Telle, S. Wall and J. Sundnes. "Modeling Cardiac Mechanics on a Sub-Cellular Scale." In Modeling Excitable Tissue: The EMI Framework, edited by A. Tveito, M. E. Rognes and K. Mardal, 28-43. Vol. 7. Cham: Springer International Publishing, 2021.PDF icon telle2021_chapter_modelingcardiacmechanicsonasub.pdf (1.72 MB)
Modeling Excitable Tissue: The EMI Framework, Edited by A. Tveito, K. Mardal and M. E. Rognes. Springer, 2021.
K. H. Jæger, K. G. Hustad, X. Cai and A. Tveito. "Operator Splitting and Finite Difference Schemes for Solving the EMI Model." In Modeling Excitable Tissue: The EMI Framework, edited by A. Tveito, K. Mardal and M. E. Rognes, 44-55. Vol. 7. Cham: Springer International Publishing, 2021.
K. H. Jæger, K. G. Hustad, X. Cai and A. Tveito. "Operator Splitting and Finite Difference Schemes for Solving the EMI Model." In Modeling Excitable Tissue: The EMI Framework, edited by A. Tveito, K. Mardal and M. E. Rognes, 44-55. Vol. 7. Cham: Springer International Publishing, 2021.
2020
A. Tveito, K. H. Jæger, M. Maleckar, W. R. Giles and S. Wall. "Computational translation of drug effects from animal experiments to human ventricular myocytes." Nature Scientific Reports (2020): 10537.
K. H. Jæger, V. Charwat, B. Charrez, H. Finsberg, M. Maleckar, S. Wall, K. E. Healy and A. Tveito. "Improved computational identification of drug response using optical measurements of human stem cell derived cardiomyocytes in microphysiological systems." Frontiers in Pharmacology 10 (2020).
2019
K. H. Jæger, S. Wall and A. Tveito. "Detecting undetectables: Can conductances of action potential models be changed without appreciable change in the transmembrane potential?" Chaos 29 (2019).
Å. Telle, B. Charrez, K. E. Healy, A. Tveito and S. Wall. Finite element modeling of cardiac tissue in heart-on-a-chip systems In Washington DC, USA., 2019.
A. P. Buccino, M. Kuchta, K. H. Jæger, T. V. Ness, P. Berthet, K. Mardal, G. Cauwenberghs and A. Tveito. "How does the presence of neural probes affect extracellular potentials?" Journal of Neural Engineering 16 (2019): 026030.
Å. Telle, B. Charrez, K. E. Healy, A. Tveito and S. Wall. A Numerical Model of Heart -on -a-Chip Systems – A Tool for Cardiotoxicity Screening In Melbourne, Australia., 2019.
Å. Telle, B. Charrez, K. E. Healy, A. Tveito and S. Wall. A numerical model of mechanical properties of cardiac tissue in heart-on-a-chip devices. Norwegian meeting on PDEs, Trondheim, Norway, 2019.PDF icon postertrondheim.pdf (1.07 MB)
K. H. Jæger, A. G. Edwards, A. D. McCulloch and A. Tveito. "Properties of cardiac conduction in a cell-based computational model." PLoS Computational Biology 15, no. 5 (2019).
2018
A. Tveito, M. Maleckar and G. T. Lines. "Computing Optimal Properties of Drugs Using Mathematical Models of Single Channel Dynamics." Computational and Mathematical Biophysics 6, no. 1 (2018): 41-64.PDF icon computing_optimal_properties_of_drugs_using_mathematical_models_of_single_channel_dynamics.pdf (1.45 MB)

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