K. Valen-Sendstad (2011)

Computational Cerebral Hemodynamics

PhD thesis, University of Oslo

Stroke is the third most common reason for death in the Western world. One type of stroke is caused by the rupture of an out-pouch of a blood vessel, called an aneurysm. As much as six per cent of us can develop aneurysms during our life time, and the number of incidences of stroke is on the rise. Understanding the underlying processes of initiation, growth and rupture of aneurysms is of great importance to both a patient and society in general. Therefore, one has to gain detailed knowledge of blood flow and its effects on the blood vessel wall. Blood flow inside aneurysms has previously been believed to be stable and smooth. However, in Valen-Sendstad's thesis, it is proven through very high-resolution computational fluid dynamics that the flow can be complex and turbulent. This means that the cells inside the blood vessels, or aneurysms, might experience forces much stronger than previously assumed.
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