AuthorsB. Y., M. Hsu, Y. Zhang, W. Wang, T. Kvamsdal, S. Hentschel and J. G. Isaksen
TitleComputational Vascular fluid-structure Interaction: Methodology and Application to Cerebral Aneurysms
AfilliationCenter for Biomedical Computing (SFF), Scientific Computing
Project(s)Center for Biomedical Computing (SFF)
StatusPublished
Publication TypeJournal Article
Year of Publication2010
JournalBiomechanics and Modeling in Mechanobiology
Volume9
Number4
Pagination481-498
Abstract

A computational vascular fluid-structure interaction framework for the simulation of patient-specific cerebral aneurysm configurations is presented. A new approach for the computation of the blood vessel tissue prestress is also described. Simulations of four patient-specific models are carried out, and quantities of hemodynamic interest such as wall shear stress and wall tension are studied to examine the relevance of fluid-structure interaction modeling when compared to the rigid arterial wall assumption. We demonstrate that flexible wall modeling plays an important role in accurate prediction of patient-specific hemodynamics. Discussion of the clinical relevance of our methods and results is provided.

DOI10.1007/s10237-010-0189-7
Citation KeySimula.sc.808