Hermenegild Arevalo
Chief Research ScientistHead of Department
- Department
- Computational Physiology
- Organisation
- Simula Research Laboratory
Publications
2024
Journal Articles
K. H. Jæger, J. D. Trotter, X. Cai, H. Arevalo and A. Tveito
Evaluating computational efforts and physiological resolution of mathematical models of cardiac tissue
Scientific Reports
L. Myklebust, M. Maleckar and H. Arevalo
Fibrosis modeling choice affects morphology of ventricular arrhythmia in non-ischemic cardiomyopathy
Frontiers in Physiology
L. Pankewitz, K. G. Hustad, S. Govil, J. C. Perry, S. Hegde, R. Tang, J. H. Omens, A. Young, A. D. McCulloch and H. Arevalo
A universal biventricular coordinate system incorporating valve annuli: Validation in congenital heart disease
Medical Image Analysis
Book Chapters
A. Bertrand, C. Yamamoto, G. Monopoli, T. Schrotter, L. Myklebust, J. J. Uv, H. Arevalo and M. Maleckar
Augmentation of Cardiac Ischemic Geometry for Improving Machine Learning Performance in Arrhythmic Risk Stratification
Computational Physiology: Simula Summer School 2023− Student Reports
2023
Journal Articles
H. Finsberg, I. G. M. van Herck, C. Daversin-Catty, H. Arevalo and S. Wall
simcardems: A FEniCS-based cardiac electro-mechanics solver
Journal of Open Source Software
Proceedings, refereed
J. J. Uv, L. Myklebust and H. Arevalo
PO-01-207 Vernix Caseosa Distribution Modulates Non-Invasive Fetal ECG Signal: A Computational Study
Heart Rhythm
Book Chapters
A. Busatto, J. Krauß, E. Kruithof, H. Arevalo and I. van Herck
Electromechanical In Silico Testing Alters Predicted Drug-Induced Risk to Develop Torsade de Pointes
Computational Physiology: Simula Summer School 2022 - Student Reports
Talks, contributed
L. Myklebust, J. J. Uv, M. Maleckar and H. Arevalo
Maximum Fibrosis Affects Reentry Morphology in 3D Ventricular Models
Computing in Cardiology
2022
Journal Articles
M. Albatat, H. Finsberg, H. Arevalo, J. Sundnes, J. Bergsland, I. Balasingham and H. H. Odland
Regional Left Ventricular Fiber Stress Analysis for Cardiac Resynchronization Therapy Response
Annals of Biomedical Engineering
Proceedings, refereed
J. J. Uv and H. Arevalo
Electrophysiological Simulation of Maternal-Fetal ECG on a 3D Maternal Torso Model
Computing in Cardiology
I. van Herck, H. Finsberg, C. Daversin-Catty, M. Mora, B. Trenor, H. Arevalo and S. Wall
Population of Computational Cell and Tissue Cardiac Electromechanical Models for functional analysis
World Congress of Biomechanics
Book Chapters
J. J. Uv, L. Myklebust, H. K. Rudsari, H. Welle and H. Arevalo
3D Simulations of Fetal and Maternal Ventricular Excitation for Investigating the Abdominal ECG
Computational Physiology - Simula Summer School 2021 - Student Reports
Talks, contributed
L. Myklebust, J. J. Uv, H. Welle and H. K. Rudsari
An image-based 3D electrophysiological torso model for simulating maternal and fetal ECG
Virtual Physiological Human Conference - VPH
L. Pankewitz, S. Govil, K. G. Hustad, J. C. Perry, S. Hedge, R. Tang, A. D. McCulloch and H. Arevalo
Development of a Biventricular Coordinate System with Representation of an Anatomically Detailed Base
Tampere
I. G. M. van Herck, J. Llopis-Lorente, H. Finsberg, C. Daversin-Catty, M. Mora, J. Saiz, B. Trenor, H. Arevalo and S. Wall
Computational 3D cardiac electromechanical models for functional and pharmacological analysis
9th International Workshop on Cardiac Mechano-Electric Coupling and Arrhythmias
I. G. M. van Herck, M. Mora, H. Finsberg, C. Daversin-Catty, B. Trenor, H. Arevalo and S. Wall
Omecamtiv Mecarbil Improves Contraction Behaviour in a 3D Electromechanical Tissue Model of Heart Failure
49th Computing in Cardiology Conference
I. G. M. van Herck, H. Finsberg, C. Daversin-Catty, M. Mora, B. Trenor, H. Arevalo and S. Wall
Functional Analysis of Healthy and Heart Failure Tissue Populations using 3D Cardiac Electromechanical Models
15th World Congress on Computational Mechanics (virtual)
Conference proceedings
I. G. M. van Herck, M. Mora, J. Llopis-Lorente, H. Finsberg, C. Daversin-Catty, J. Saiz, B. Trenor, H. Arevalo and S. Wall
Omecamtiv Mecarbil Improves Contraction Behaviour in a 3D Electromechanical Tissue Model of Heart Failure
2022 Computing in Cardiology (CinC)
2021
Journal Articles
M. Maleckar, L. Myklebust, J. J. Uv, P. M. Florvaag, V. Strøm, C. Glinge, R. Jabbari, N. Vejlstrup, T. Engstrøm, K. Ahtarovski, T. Jespersen, J. Tfelt-Hansen and H. Arevalo
Combined In-silico and Machine Learning Approaches Toward Predicting Arrhythmic Risk in Post-infarction Patients
Frontiers in physiology
M. Vagos, H. Arevalo, J. Heijman, U. Schotten and J. Sundnes
A computational study of the effects of tachycardia-induced remodelling on calcium wave propagation in rabbit atrial myocytes
Frontiers in Physiology
M. Albatat, H. Arevalo, J. Bergsland, V. Strøm, I. Balasingham and H. H. Odland
Optimal pacing sites in cardiac resynchronization by left ventricular activation front analysis
Computers in Biology and Medicine
Posters
M. Maleckar, P. M. Florvaag, V. Strøm, C. Glinge, R. Jabbari, N. Vejlstrup, T. Engstrom, K. A. Ahtarovski, T. Jespersen, J. Tfelt-Hansen and H. Arevalo
B-PO02-022 Combining simulation and machine learning to accurately predict arrhythmic risk in post-infarction patients
Heart Rhythm
2020
Journal Articles
M. Albatat, H. Finsberg, H. Arevalo, J. Sundnes, J. Bergsland, I. Balasingham and H. H. Odland
Regional Left Ventricular Fiber Stress Analysis for Cardiac Resynchronization Therapy Response
Journal of Cardiovascular Electrophysiology
J. Dhamala, P. Bajracharya, H. Arevalo, J. L. Sapp, M. Horácek, K. C. Wu, N. A. Trayanova and L. Wang
Embedding high-dimensional Bayesian optimization via generative modeling: Parameter personalization of cardiac electrophysiological models
Medical Image Analysis
M. Vagos, H. Arevalo, J. Heijman, U. Schotten and J. Sundnes
A novel computational model of the rabbit atrial cardiomyocyte with spatial calcium dynamics
Frontiers in Physiology
M. Albatat, J. Bergsland, H. Arevalo, H. H. Odland, S. Wall, J. Sundnes and I. Balasingham
Multisite pacing and myocardial scars: a computational study
Computer Methods in Biomechanics and Biomedical Engineering
M. Albatat, J. Bergsland, H. Arevalo, H. H. Oddland, P. Bose, P. S. Halvorsen and I. Balasingham
Technological and Clinical Challenges in Lead Placement for Cardiac Rhythm Management Devices
Annals of Biomedical Engineering
Proceedings, refereed
T. P. Walz, L. Azzolin, L. Berg, E. Chleilat and H. Arevalo
Potential Roles of Purkinje Fibers in Ischemia-Induced Arrhythmias
Computing in Cardiology
Posters
J. Langguth, N. Gaur, H. Arevalo, C. Jarvis, N. Altanaite, Q. Lan and X. Cai
Towards detailed Organ-Scale Simulations in Cardiac Electrophysiology
K. G. Hustad, X. Cai, J. Langguth and H. Arevalo
Efficient simulations of patient-specific electrical heart activity on the DGX-2
Patents
F. Vadakkumpadan, H. Arevalo, N. A. Trayanova and K. Wu
System and method for personalized cardiac arrhythmia risk assessment by simulating arrhythmia inducibility
N. A. Trayanova, H. R. Halperin, H. Arevalo and J. Constantino
System and method for planning a patient-specific cardiac procedure
2019
Proceedings, refereed
J. Langguth, H. Arevalo and X. Cai
Towards Detailed Real-Time Simulations of Cardiac Arrhythmia
Computing in Cardiology
H. Arevalo, K. H. Jæger and S. Wall
Investigating the Pro- and Anti-Arrhythmic Properties of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes in Post-Infarction Patient Hearts: A Modeling Study
6th International Conference on Computational and Mathematical Biomedical Engineering
Posters
J. Langguth, H. Arevalo, K. G. Hustad and X. Cai
Towards Detailed Real-Time Simulations of Cardiac Arrhythmia
Talks, contributed
P. M. Florvaag, V. Strøm, C. Glinge, R. Jabbari, N. Vejlstrup, T. Engstrom, K. A. Ahtarovski, T. Jespersen, J. Tfelt-Hansen, V. Naumova and H. Arevalo
A Combined In-Silico and Machine Learning Approach towards Predicting Arrhythmic Risk in Post-Infarction Patients
Computing in Cardiology, Singapore
2018
Journal Articles
I. van Herck, B. H. Bentzen, V. Seutin, H. Arevalo, M. Maleckar, N. Marrion and A. G. Edwards
Model development of sk channel gating incorporating calcium sensitivity and drug interaction
Biophysical Journal
M. R. Vagos, J. Heijman, H. Arevalo, M. Maleckar, B. L. de Oliveira, U. Schotten and J. Sundnes
A Novel Computational Model of the Rabbit Atrial Myocyte Offers Insight into Calcium Wave Propagation Failure
Biophysical Journal
D. Deng, P. P. Nikolov, H. Arevalo and N. A. Trayanova
Optimal contrast-enhanced MRI image thresholding for accurate prediction of ventricular tachycardia using ex-vivo high resolution models
Computers in biology and medicine
A. Prakosa, H. Arevalo, D. Deng, P. M. Boyle, P. P. Nikolov, H. Ashikaga, J. J. E. Blauer, E. Ghafoori, C. J. Park, R. C. Blake, F. T. Han, R. S. MacLeod, H. R. Halperin, D. J. Callans, R. Ranjan, J. Chrispin, S. Nazarian and N. A. Trayanova
Personalized virtual-heart technology for guiding the ablation of infarct-related ventricular tachycardia
Nature Biomedical Engineering
M. Vagos, I. G. M. van Herck, J. Sundnes, H. Arevalo, A. G. Edwards and J. Koivumäki
Computational Modeling of Electrophysiology and Pharmacotherapy of Atrial Fibrillation: Recent Advances and Future Challenges
Frontiers in Physiology
J. Dhamala, H. Arevalo, J. Sapp, M. Horácek, K. C. Wu, N. A. Trayanova and L. Wang
Quantifying the uncertainty in model parameters using Gaussian process-based Markov chain Monte Carlo in cardiac electrophysiology
Medical Image Analysis
Proceedings, refereed
M. Albatat, R. King, L. Unger, H. Arevalo, S. Wall, J. Sundnes, J. Bergsland and I. Balasingham
Electromechanical Model to Predict Cardiac Resynchronization Therapy
2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)
Posters
I. G. M. van Herck, B. H. Bentzen, V. Seutin, H. Arevalo, M. Maleckar, N. Marrion and A. G. Edwards
Model development of SK channel gating incorporating calcium sensitivity and drug interaction
M. Vagos, J. Heijman, H. Arevalo, M. Maleckar, B. L. de Oliveira, U. Schotten and J. Sundnes
A Novel Computational Model of the Rabbit Atrial Myocyte Offers Insight into Calcium Wave Propagation Failure
Biophysical Journal
Conference proceedings
M. Albatat, R. King, L. Unger, H. Arevalo, S. Wall, J. Sundnes, J. Bergsland and I. Balasingham
Electromechanical model to predict cardiac resynchronization therapy
40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
2017
Journal Articles
M. R. Vagos, H. Arevalo, B. L. de Oliveira, J. Sundnes and M. Maleckar
A computational framework for testing arrhythmia marker sensitivities to model parameters in functionally calibrated populations of atrial cells
Chaos: An Interdisciplinary Journal of Nonlinear Science
Proceedings, refereed
M. Marciniak, H. Arevalo, J. Tfelt-Hansen, K. A. Ahtarovski, T. Jespersen, R. Jabbari, C. Glinge, N. Vejlstrup, T. Engstrom, M. Maleckar and o.
A multiple kernel learning framework to investigate the relationship between ventricular fibrillation and first myocardial infarction
International Conference on Functional Imaging and Modeling of the Heart
Posters
I. G. M. van Herck, R. S. Vicens, H. Arevalo, J. Koivumäki, B. H. Bentzen and A. G. Edwards
Small conductance calcium activated potassium channel: pharmacology and binding scheme for in silico model
2016
Proceedings, refereed
M. Marciniak, H. Arevalo, J. Tfelt-Hansen, T. Jespersen, R. Jabbari, C. Glinge, K. A. Ahtarovski, N. Vejlstrup, T. Engstrom and M. Maleckar
From CMR image to patient-specific simulation and population-based analysis: tutorial for an openly available image-processing pipeline
International Workshop on Statistical Atlases and Computational Models of the Heart