Karoline Horgmo Jæger

K. H. Jæger and A. Tveito

Electrodiffusion dynamics in the cardiomyocyte dyad at nano-scale resolution using the Poisson-Nernst-Planck (PNP) equations

PLOS Computational Biology

K. H. Jæger, V. Charwat, K. Healy, S. Wall and A. Tveito

Determining properties of human-induced pluripotent stem cell-derived cardiomyocytes using spatially resolved electromechanical metrics

The Journal of Physiology

K. H. Jæger and A. Tveito

A possible path to persistent re-entry waves at the outlet of the left pulmonary vein

npj Systems Biology and Applications

K. H. Jæger, J. D. Trotter, X. Cai, H. Arevalo and A. Tveito

Evaluating computational efforts and physiological resolution of mathematical models of cardiac tissue

Scientific Reports

K. H. Jæger, V. Charwat, S. Wall, K. Healy and A. Tveito

Do calcium channel blockers applied to cardiomyocytes cause increased channel expression resulting in reduced efficacy?

npj Systems Biology and Applications

K. H. Jæger and A. Tveito

The simplified Kirchhoff network model (SKNM): a cell‐based reaction–diffusion model of excitable tissue

Scientific Reports

K. H. Jæger and A. Tveito

Efficient, cell-based simulations of cardiac electrophysiology; The Kirchhoff Network Model (KNM)

npj Systems Biology and Applications

K. H. Jæger, E. Ivanovic, J. P. Kucera and A. Tveito

Nano-scale solution of the Poisson-Nernst-Planck (PNP) equations in a fraction of two neighboring cells reveals the magnitude of intercellular electrochemical waves

PLoS Computational Biology

K. H. Jæger and A. Tveito

Differential Equations for Studies in Computational Electrophysiology

Simula SpringerBriefs on Computing

V. Charwat, B. Charrez, B. A. Siemons, H. Finsberg, K. H. Jæger, A. G. Edwards, N. Huebsch, S. Wall, E. Miller, A. Tveito and K. E. Healy

Validating the Arrhythmogenic Potential of High-, Intermediate-, and Low-Risk Drugs in a Human-Induced Pluripotent Stem Cell-Derived Cardiac Microphysiological System

ACS Pharmacology & Translational Science

N. Huebsch, B. Charrez, G. Neiman, B. Siemons, S. C. Boggess, S. Wall, V. Charwat, K. H. Jæger, D. Cleres, Å. Telle, F. T. Lee-Montiel, N. C. Jeffreys, N. Deveshwar, A. G. Edwards, J. Serrano, M. Snuderl, A. Stahl, A. Tveito, E. W. Miller and K. E. Healy

Metabolically driven maturation of human-induced-pluripotent-stem-cell-derived cardiac microtissues on microfluidic chips

Nature Biomedical Engineering

K. H. Jæger, A. G. Edwards, W. R. Giles and A. Tveito

Arrhythmogenic influence of mutations in a myocyte‑based computational model of the pulmonary vein sleeve

Nature Scientific Reports

K. H. Jæger and A. Tveito

Deriving the Bidomain Model of Cardiac Electrophysiology From a Cell-Based Model; Properties and Comparisons

Frontiers in Physiology

K. H. Jæger, A. G. Edwards, W. R. Giles and A. Tveito

From Millimeters to Micrometers; Re-introducing Myocytes in Models of Cardiac Electrophysiology

Frontiers in Physiology

K. H. Jæger, A. G. Edwards, W. R. Giles and A. Tveito

A computational method for identifying an optimal combination of existing drugs to repair the action potentials of SQT1 ventricular myocytes

PLoS Computational Biology

K. H. Jæger, V. Charwat, S. Wall, K. E. Healy and A. Tveito

Identifying drug response by combining measurements of the membrane potential, the cytosolic calcium concentration, and the extracellular potential in microphysiological systems

Frontiers in Pharmacology

K. H. Jæger, S. Wall and A. Tveito

Computational prediction of drug response in short QT syndrome type 1 based on measurements of compound effect in stem cell-derived cardiomyocytes

PLoS Computational Biology

K. H. Jæger, K. G. Hustad, X. Cai and A. Tveito

Efficient numerical solution of the EMI model representing the extracellular space (E), cell membrane (M) and intracellular space (I) of a collection of cardiac cells

Frontiers in Physics

K. H. Jæger, K. G. Hustad, X. Cai and A. Tveito

Operator Splitting and Finite Difference Schemes for Solving the EMI Model

Modeling Excitable Tissue: The EMI Framework

K. H. Jæger and A. Tveito

Derivation of a Cell-Based Mathematical Model of Excitable Cells

Modeling Excitable Tissue: The EMI Framework

A. Tveito, K. H. Jæger, M. Maleckar, W. R. Giles and S. Wall

Computational translation of drug effects from animal experiments to human ventricular myocytes

Nature Scientific Reports

K. H. Jæger, V. Charwat, B. Charrez, H. Finsberg, M. Maleckar, S. Wall, K. E. Healy and A. Tveito

Improved computational identification of drug response using optical measurements of human stem cell derived cardiomyocytes in microphysiological systems

Frontiers in Pharmacology

A. P. Buccino, M. Kuchta, K. H. Jæger, T. V. Ness, P. Berthet, K. Mardal, G. Cauwenberghs and A. Tveito

How does the presence of neural probes affect extracellular potentials?

Journal of Neural Engineering

K. H. Jæger, A. G. Edwards, A. D. McCulloch and A. Tveito

Properties of cardiac conduction in a cell-based computational model

PLoS Computational Biology

K. H. Jæger, S. Wall and A. Tveito

Detecting undetectables: Can conductances of action potential models be changed without appreciable change in the transmembrane potential?

Chaos

H. Arevalo, K. H. Jæger and S. Wall

Investigating the Pro- and Anti-Arrhythmic Properties of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes in Post-Infarction Patient Hearts: A Modeling Study

6th International Conference on Computational and Mathematical Biomedical Engineering

K. H. Jæger

Cell-Based Mathematical Models of Small Collections of Excitable Cells

The University of Oslo

A. Tveito, K. H. Jæger, N. Huebsch, B. Charrez, A. G. Edwards, S. Wall and K. E. Healy

Inversion and computational maturation of drug response using human stem cell derived cardiomyocytes in microphysiological systems

Nature Scientific Reports

S. Wall, K. H. Jæger, N. Huebsch, B. Charrez, K. Healy and A. Tveito

In Silico - Augmented Cardiac Microphysiological Systems for Evaluating Cardiac Drug Effects

S. Wall, K. H. Jæger, N. Huebsch, B. Charrez, K. Healy and A. Tveito

In Silico - Augmented Cardiac Microphysiological Systems for Evaluating Cardiac Drug Effects

S. Wall, A. Tveito, K. H. Jæger, A. G. Edwards, K. Healy, N. Huebsch and B. Charrez

In Silico Modeling of Cardiac Microphysiological Systems for Evaluating Drug Side Effects

Heart By Numbers Conference, Berlin, Germany

A. Tveito, K. H. Jæger, M. Kuchta, K. Mardal and M. E. Rognes

A cell-based framework for numerical modelling of electrical conduction in cardiac tissue

Frontiers in Physics, Computational Physics

A. Tveito, K. H. Jæger, G. T. Lines, Ł. Paszkowski, J. Sundnes, A. G. Edwards, T. Mäki-Marttunen, G. Halnes and G. T. Einevoll

An Evaluation of the Accuracy of Classical Models for Computing the Membrane Potential and Extracellular Potential for Neurons

Frontiers in Computational Neuroscience

K. H. Jæger

An Investigation of Necessary Grid Resolution for Numerical Simulations of Calcium Dynamics in Cardiac Cells

The University of Oslo