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K. J. McCabe

Computational Physiology: Simula Summer School 2021 − Student Reports

In Simula SpringerBriefs on Computing. Vol. 12. Cham: Springer, 2022.
Edited books
2022
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M. H. Mesa, J. van den Brink, W. E. Louch, K. J. McCabe and P. Rangamani

Nanoscale organization of ryanodine receptor distribution and phosphorylation pattern determines the dynamics of calcium sparks

PLOS Computational Biology 18, no. 6 (2022): e1010126.
Journal Article
2022
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K. J. McCabe and P. Rangamani

Computational modeling approaches to cAMP/PKA signaling in cardiomyocytes

Journal of Molecular and Cellular Cardiology 154 (2021): 32-40.
Journal Article
2021
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K. J. McCabe, Y. Aboelkassem, A. Teitgen, G. Huber, A. J. McCammon, M. Regnier and A. D. McCulloch

Predicting the effects of dATP on cardiac contraction using multiscale modeling of the sarcomere

Archives of Biochemistry and Biophysics 695 (2020): 108582.
Journal Article
2020
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News

31 March 2023

New book in the SpringerBriefs series: Computational Physiology - Simula Summer School 2022 - Student Reports

Background

PhD, Bioengineering
University of California, San Diego
April 2019
MSc, Bioengineering
University of California, San Diego
December 2016
BSc, Biomedical Engineering
Yale University
May 2013

Awards

Engelson Ph.D. Thesis Award in Bioengineering
University of California, San Diego
June 2019
Siebel Scholar, Class of 2019
University of California, San Diego
August 2018

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Export 13 results:
2022

Journal articles

M. H. Mesa, J. van den Brink, W. E. Louch, K. J. McCabe and P. Rangamani

Nanoscale organization of ryanodine receptor distribution and phosphorylation pattern determines the dynamics of calcium sparks

PLOS Computational Biology 18, no. 6 (2022): e1010126.
Status: Published

Edited books

K. J. McCabe

Computational Physiology: Simula Summer School 2021 − Student Reports

In Simula SpringerBriefs on Computing. Vol. 12. Cham: Springer, 2022.
Status: Published
2021

Journal articles

K. J. McCabe and P. Rangamani

Computational modeling approaches to cAMP/PKA signaling in cardiomyocytes

Journal of Molecular and Cellular Cardiology 154 (2021): 32-40.
Status: Published
2020

Journal articles

K. J. McCabe, Y. Aboelkassem, A. Teitgen, G. Huber, A. J. McCammon, M. Regnier and A. D. McCulloch

Predicting the effects of dATP on cardiac contraction using multiscale modeling of the sarcomere

Archives of Biochemistry and Biophysics 695 (2020): 108582.
Status: Published

Talks, contributed

K. J. McCabe, Y. Aboelkassem, A. Teitgen, M. Regnier and A. D. McCulloch

Multiscale modelling determines mechanisms of action for 2'-deoxy-ATP, a myosin activating therapeutic for heart failure

In VPH 2020, Paris, France (Virtual). VPH 2020, 2020.
Status: Published
2019

Journal articles

Y. Aboelkassem, K. J. McCabe, G. Huber, M. Regnier, A. J. McCammon and A. D. McCulloch

A Stochastic Multiscale Model of Cardiac Thin Filament Activation Using Brownian-Langevin Dynamics

Biophysical Journal 117, no. 12 (2019): 2255-2272.
Status: Published
Y. Aboelkassem, J. D. Powers, K. J. McCabe and A. D. McCulloch

Multiscale Models of Cardiac Muscle Biophysics and Tissue Remodeling in Hypertrophic Cardiomyopathies

Current Opinion in Biomedical Engineering 11 (2019): 35-44.
Status: Published
J. D. Powers, C. Yuan, K. J. McCabe, J. D. Murray, M. C. Childers, G. V. Flint, F. Moussavi-Harami, S. Mohran, R. Castillo, C. Zuzek et al.

Cardiac myosin activation with 2-deoxy-ATP via increased electrostatic interactions with actin

Proceedings of the National Academy of Sciences (2019).
Status: Published
2018

Posters

Y. Aboelkassem, K. J. McCabe, G. Huber, J. Sundnes and A. D. McCulloch

Turning the Azimuthal Motions of Adjacent Tropomyosins into a Coupled N-body Problem in a Brownian Model of Cardiac Thin Filament Activation

In Biophysical Journal. San Francisco, California/U.S.A.: Elsevier, 2018.
Status: Published
K. J. McCabe, Y. Aboelkassem, S. Dewan, M. Regnier and A. D. McCulloch

A Markov State Model of the Sarcomere to Explain the Effects of dATP on Cardiac Contraction

Biophysical Society 62nd Annual Meeting, San Francisco CA, 2018.
Status: Published