AuthorsE. M. Arruda, S. Calve, K. Garikipati, K. Grosh and H. Narayanan
EditorsG. A. Holzapfel and R. W. Ogden
TitleCharacterization and Modeling of Growth and Remodeling in Tendon and Soft Tissue Constructs
StatusPublished
Publication TypeBook Chapter
Year of Publication2006
Book TitleMechanics of Biological Tissue
Chapter5
Pagination63-75
PublisherSpringer
ISBN Number978-3-540-25194-1
Abstract

Separate theories of growth and remodeling have been outlined to illustrate that remodeling may occur at constant mass and is a configurational change whereas growth involves a change in the concentration of species. Engineered tendon constructs were generated for growth and remodeling studies. The constructs demonstrate mechanically responsive cells, grow and remain viable in culture for several weeks. They are excellent in vitro models for growth studies.

DOI10.1007/3-540-31184-X\_5