|Editors||H. Finsberg, M. E. Rognes, J. Sundnes, S. Wall, H. H. Odland and S. Ross|
|Title||Dyssynchronous Left Ventricular Stress Estimation|
|Afilliation||Scientific Computing, , Scientific Computing|
|Project(s)||Center for Biomedical Computing (SFF)|
|Publication Type||Talks, invited|
|Year of Publication||2015|
|Location of Talk||Workshop on Advanced Numerical Techniques in Biomedical Computing: Simula Research Laboratory|
The heart is a muscular pump that moves approximatly 8,000 litres per day through the human body. It manages to this by a combination of contraction/relaxation along muscle fibers and elastic recoil. These two effects are indistinguishable in a medical image, but can be estimated using a computational model.
In our work we use adjoint based optimization techniques in order to determine muscle contraction and elastic recoil in a patient specific left ventricular geometry based on echocardiography and pressure catheter data. Possible applications of the technique include mechanical stress estimation and hypothesis testing in cardiac resynchronization therapy research.