AuthorsS. A. Niederer, E. Kerfoot, A. Benson, M. Bernabeu, O. Bernus, E. Cherry, R. Clayton, F. Fenton, A. Garny, E. Heidenreich et al.
TitleN-Version Benchmark Evaluation of Cardiac Tissue Electrophysiology Simulators
AfilliationCenter for Biomedical Computing (SFF), Cardiac Modeling, Scientific Computing
Project(s)Center for Biomedical Computing (SFF)
StatusPublished
Publication TypeJournal Article
Year of Publication2011
JournalPhilosophical Transactions of the Royal Society A
Volume369
Number1954
Pagination4331-51
Date PublishedNovember
Abstract

Ongoing developments in cardiac modelling have resulted, in particular, in the development of advanced and increasingly complex computational frameworks for simulating cardiac tissue electrophysiology. The goal of these simulations is often to represent the detailed physiology and pathologies of the heart using codes that exploit the computational potential of high-performance computing architectures. These developments have rapidly progressed the simulation capacity of cardiac virtual physiological human style models; however, they have also made it increasingly challenging to verify that a given code provides a faithful representation of the purported governing equations and corresponding solution techniques. This study provides the first cardiac tissue electrophysiology simulation benchmark to allow these codes to be verified. The benchmark was successfully evaluated on 11 simulation platforms to generate a consensus gold-standard converged solution. The benchmark definition in combination with the gold-standard solution can now be used to verify new simulation codes and numerical methods in the future.

DOI10.1098/rsta.2011.0139
Citation KeySimula.simula.230