AuthorsM. Causemann, V. Vinje and M. E. Rognes
TitleThe pulsating brain: an interface-coupled fluid-poroelastic model of the cranial cavity
AfilliationScientific Computing
Project(s)Exciting times: Extreme modelling of excitable tissue (EMIx), Department of Numerical Analysis and Scientific Computing
Publication TypeTalks, contributed
Year of Publication2022
Location of TalkECCOMAS Congress 2022, Oslo, Norway
Keywordsbrain mechanics, Finite element method, interface coupling, multiphysics problems

Driven by cardiac and respiratory pulsations, our brain and the cerebrospinal (CSF) fluid
surrounding it exhibit complex fluid flow and displacement patterns. Despite being essen-
tial to normal brain function, our understanding of intracranial dynamics is still limited,
and various diseases are associated with impaired CSF flow and elevated intracranial pres-
sure [1]. Computational models offer further insights into pulsatile intracranial dynamics,
but are complicated by the close interplay of arterial inflow, venous outflow, CSF motion
and brain tissue movement inside the rigid cranial cavity.
In this talk, I will present a new computational model of cardiac-induced pulsatile motion
inside the human cranial cavity. The CSF flow in the subarachnoid space and ventricular
system is modelled using the time-dependent Stokes equations, and coupled with Biot’s
poroelasticity equations in the brain tissue, thus integrating all major intracranial con-
stituents into the modelling approach. Employing the pulsatile inflow of blood into brain
tissue as a driver of motion, the model enables us to study the dynamics of the entire
intracranial system.
The model is discretized using a coupled/monolithic approach with a mixed
Taylor-Hood type finite element scheme and implemented with the finite element frame-
work FEniCS. Numerical results obtained with a detailed 3D human head model and
physiological material parameters are presented and compared with experimental data.
The new model faithfully replicates the main aspects of intracranial pulsatile motion.

Citation Key42942

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