K. G. Jebsen Centre for Brain Fluid Research
The centre is led by UiO Professor Per Kristian Eide, and Simula Chief Research Scientist Marie E. Rognes is its Deputy Director.
“We are very excited to receive this recognition and support of our research and consortium from the K.G. Jebsen Foundation,” says Marie E. Rognes.
“Our Centre for Brain Fluid Research builds on a decade of groundbreaking joint research in the mathematical sciences and basic neurosciences, and we will together translate these discoveries to clinical medicine, targeting new diagnostics and therapies for dementia and brain cancer.”
The new centre, named K.G. Jebsen Centre for Brain Fluid Research, is hosted and led by the University of Oslo and Oslo University Hospital with Simula as a major partner.
Simula's role and the "best of both worlds"
The centre has three main research goals: to provide imaging- and blood-based biomarkers for precision diagnosis of dementia, to provide new tools for precision treatment of brain cancer, and to give fundamental understanding of the mechanisms underlying brain solute transport and clearance. New computational mathematics, including physics-based models, simulation technology, and artificial intelligence, underpins all three research objectives.
Simula will lead the centre’s activities in computational and translational mathematics.
“We aim to develop personalised computational models integrating MR imaging data and prior knowledge of brain clearance. By combining artificial intelligence and data-driven techniques with brain physics-based mathematical models, we hope to take advantage of ‘the best of both worlds’,” says Rognes.
Funding
The K.G. Jebsen Foundation (kgjf.org) has a long-term view as far as supportive innovative approaches, acknowledging that making a difference can take many years to achieve. Based on its independent due diligence, the foundation has an overall aim to enhance the well-being of people and promote human and social development, through the support of grantees in the areas of health, education, science, culture, and the environment around the world.
The partners in the centre
- Per Kristian Eide, Centre Director, Professor and senior consultant neurosurgeon at the Department of Neurosurgey, Oslo University Hospital (OUS) and Institute of Clinical Medicine, University of Oslo (UiO).
- Marie E. Rognes, Deputy Director, Chief Research Scientist at Simula Research Laboratory
- Kyrre Eeg Emblem, Head of the Department of Physics and Imaging Analysis, OUS
- Rune Enger, Associate Professor and Doctor at the Division of Anatomy, Institute of Basic Medical Sciences, UiO
- Susanne Sørensen Hernes, Geriatrician and Associate Professor at the Department of Clinical Science, University of Bergen, and Sørlandet Hospital
- Kent-Andre Mardal, Professor at the Department of Mathematics, UiO and Adjunct Research Scientist at Simula Research Laboratory
- Geir Ringstad, Section Leader and consultant neuroradiologist at the Department of Radiology, OuS-Rikshospitalet.