Aslak Tveito
ProfessorSimula Fellow
- Department
- Computational Physiology
- Organisation
- Simula Research Laboratory
- Research Interests
- Computational physiology Biophysics Scientific computing
![Aslak Tveito](/_next/image?url=%2Fimages%2Fperson-placeholder.png&w=384&q=75)
- aslak@simula.no
Publications
2024
Journal Articles
K. H. Jæger, V. Charwat, S. Wall, K. Healy and A. Tveito
Do calcium channel blockers applied to cardiomyocytes cause increased channel expression resulting in reduced efficacy?
npj Systems Biology and Applications
2023
Journal Articles
K. H. Jæger and A. Tveito
The simplified Kirchhoff network model (SKNM): a cell‐based reaction–diffusion model of excitable tissue
Scientific Reports
K. H. Jæger and A. Tveito
Efficient, cell-based simulations of cardiac electrophysiology; The Kirchhoff Network Model (KNM)
npj Systems Biology and Applications
K. H. Jæger, E. Ivanovic, J. P. Kucera and A. Tveito
Nano-scale solution of the Poisson-Nernst-Planck (PNP) equations in a fraction of two neighboring cells reveals the magnitude of intercellular electrochemical waves
PLoS Computational Biology
Books
K. H. Jæger and A. Tveito
Differential Equations for Studies in Computational Electrophysiology
Simula SpringerBriefs on Computing
2022
Journal Articles
V. Charwat, B. Charrez, B. A. Siemons, H. Finsberg, K. H. Jæger, A. G. Edwards, N. Huebsch, S. Wall, E. Miller, A. Tveito and K. E. Healy
Validating the Arrhythmogenic Potential of High-, Intermediate-, and Low-Risk Drugs in a Human-Induced Pluripotent Stem Cell-Derived Cardiac Microphysiological System
ACS Pharmacology & Translational Science
N. Huebsch, B. Charrez, G. Neiman, B. Siemons, S. C. Boggess, S. Wall, V. Charwat, K. H. Jæger, D. Cleres, Å. Telle, F. T. Lee-Montiel, N. C. Jeffreys, N. Deveshwar, A. G. Edwards, J. Serrano, M. Snuderl, A. Stahl, A. Tveito, E. W. Miller and K. E. Healy
Metabolically driven maturation of human-induced-pluripotent-stem-cell-derived cardiac microtissues on microfluidic chips
Nature Biomedical Engineering
K. H. Jæger, A. G. Edwards, W. R. Giles and A. Tveito
Arrhythmogenic influence of mutations in a myocyte‑based computational model of the pulmonary vein sleeve
Nature Scientific Reports
K. H. Jæger and A. Tveito
Deriving the Bidomain Model of Cardiac Electrophysiology From a Cell-Based Model; Properties and Comparisons
Frontiers in Physiology
2021
Journal Articles
K. H. Jæger, A. G. Edwards, W. R. Giles and A. Tveito
From Millimeters to Micrometers; Re-introducing Myocytes in Models of Cardiac Electrophysiology
Frontiers in Physiology
K. H. Jæger, A. G. Edwards, W. R. Giles and A. Tveito
A computational method for identifying an optimal combination of existing drugs to repair the action potentials of SQT1 ventricular myocytes
PLoS Computational Biology
K. H. Jæger, V. Charwat, S. Wall, K. E. Healy and A. Tveito
Identifying drug response by combining measurements of the membrane potential, the cytosolic calcium concentration, and the extracellular potential in microphysiological systems
Frontiers in Pharmacology
K. H. Jæger, S. Wall and A. Tveito
Computational prediction of drug response in short QT syndrome type 1 based on measurements of compound effect in stem cell-derived cardiomyocytes
PLoS Computational Biology
K. H. Jæger, K. G. Hustad, X. Cai and A. Tveito
Efficient numerical solution of the EMI model representing the extracellular space (E), cell membrane (M) and intracellular space (I) of a collection of cardiac cells
Frontiers in Physics
Book Chapters
Å. Telle, S. Wall and J. Sundnes
Modeling Cardiac Mechanics on a Sub-Cellular Scale
Modeling Excitable Tissue: The EMI Framework
M. Kuchta and K. Mardal
Iterative Solvers for EMI Models
Modeling Excitable Tissue: The EMI Framework
A. P. Buccino, M. Kuchta, J. Schreiner and K. Mardal
Improving Neural Simulations with the EMI Model
Modeling Excitable Tissue: The EMI Framework
M. Kuchta, K. Mardal and M. E. Rognes
Solving the EMI Equations using Finite Element Methods
Modeling Excitable Tissue: The EMI Framework
K. H. Jæger, K. G. Hustad, X. Cai and A. Tveito
Operator Splitting and Finite Difference Schemes for Solving the EMI Model
Modeling Excitable Tissue: The EMI Framework
K. H. Jæger and A. Tveito
Derivation of a Cell-Based Mathematical Model of Excitable Cells
Modeling Excitable Tissue: The EMI Framework
A. J. Ellingsrud, C. Daversin-Catty and M. E. Rognes
A cell-based model for ionic electrodiffusion in excitable tissue
Modeling Excitable Tissue: The EMI Framework
Edited books
Modeling Excitable Tissue: The EMI Framework
2020
Journal Articles
A. Tveito, K. H. Jæger, M. Maleckar, W. R. Giles and S. Wall
Computational translation of drug effects from animal experiments to human ventricular myocytes
Nature Scientific Reports
K. H. Jæger, V. Charwat, B. Charrez, H. Finsberg, M. Maleckar, S. Wall, K. E. Healy and A. Tveito
Improved computational identification of drug response using optical measurements of human stem cell derived cardiomyocytes in microphysiological systems
Frontiers in Pharmacology
2019
Journal Articles
A. P. Buccino, M. Kuchta, K. H. Jæger, T. V. Ness, P. Berthet, K. Mardal, G. Cauwenberghs and A. Tveito
How does the presence of neural probes affect extracellular potentials?
Journal of Neural Engineering
K. H. Jæger, A. G. Edwards, A. D. McCulloch and A. Tveito
Properties of cardiac conduction in a cell-based computational model
PLoS Computational Biology
K. H. Jæger, S. Wall and A. Tveito
Detecting undetectables: Can conductances of action potential models be changed without appreciable change in the transmembrane potential?
Chaos
Posters
Å. Telle, B. Charrez, K. E. Healy, A. Tveito and S. Wall
A numerical model of mechanical properties of cardiac tissue in heart-on-a-chip devices
Talks, contributed
Å. Telle, B. Charrez, K. E. Healy, A. Tveito and S. Wall
A Numerical Model of Heart -on -a-Chip Systems – A Tool for Cardiotoxicity Screening
Melbourne, Australia
Å. Telle, B. Charrez, K. E. Healy, A. Tveito and S. Wall
Finite element modeling of cardiac tissue in heart-on-a-chip systems
Washington DC, USA
2018
Journal Articles
N. Huebsch, B. Charrez, B. Siemons, S. C. Boggess, S. Wall, V. Charwat, K. Jaeger, F. L. T. Montiel, N. C. Jeffreys, N. Deveshwar, A. G. Edwards, J. Serrano, M. Snuderl, A. Stahl, A. Tveito, E. W. Miller and K. E. Healy
Metabolically-Driven Maturation of hiPSC-Cell Derived Heart-on-a-Chip
{bioRxiv
A. Tveito, M. Maleckar and G. T. Lines
Computing Optimal Properties of Drugs Using Mathematical Models of Single Channel Dynamics
Computational and Mathematical Biophysics
A. Tveito, K. H. Jæger, N. Huebsch, B. Charrez, A. G. Edwards, S. Wall and K. E. Healy
Inversion and computational maturation of drug response using human stem cell derived cardiomyocytes in microphysiological systems
Nature Scientific Reports
Posters
S. Wall, K. H. Jæger, N. Huebsch, B. Charrez, K. Healy and A. Tveito
In Silico - Augmented Cardiac Microphysiological Systems for Evaluating Cardiac Drug Effects
S. Wall, K. H. Jæger, N. Huebsch, B. Charrez, K. Healy and A. Tveito
In Silico - Augmented Cardiac Microphysiological Systems for Evaluating Cardiac Drug Effects
Talks, contributed
S. Wall, A. Tveito, K. H. Jæger, A. G. Edwards, K. Healy, N. Huebsch and B. Charrez
In Silico Modeling of Cardiac Microphysiological Systems for Evaluating Drug Side Effects
Heart By Numbers Conference, Berlin, Germany
2017
Journal Articles
T. Mäki-Marttunen, G. T. Lines, A. G. Edwards, A. Tveito, A. M. Dale, G. T. Einevoll and O. A. Andreassen
Pleiotropic effects of schizophrenia-associated genetic variants in neuron firing and cardiac pacemaking revealed by computational modeling
Translational Psychiatry
A. Tveito, K. H. Jæger, M. Kuchta, K. Mardal and M. E. Rognes
A cell-based framework for numerical modelling of electrical conduction in cardiac tissue
Frontiers in Physics, Computational Physics
A. Tveito, K. H. Jæger, G. T. Lines, Ł. Paszkowski, J. Sundnes, A. G. Edwards, T. Mäki-Marttunen, G. Halnes and G. T. Einevoll
An Evaluation of the Accuracy of Classical Models for Computing the Membrane Potential and Extracellular Potential for Neurons
Frontiers in Computational Neuroscience
2016
Journal Articles
A. Tveito, G. T. Lines, A. G. Edwards and A. D. McCulloch
Computing rates of Markov models of voltage-gated ion channels by inverting partial differential equations governing the probability density functions of the conducting and non-conducting states
Mathematical Biosciences
Books
A. Tveito and G. T. Lines
Computing characterizations of drugs for ion channels and receptors using Markov models
2015
Book Chapters
A. Tveito, H. P. Langtangen and R. Winther
Computational Partial Differential Equations
Encyclopedia of Applied and Computational Mathematics
H. P. Langtangen, U. Rüde and A. Tveito
Scientific Computing
Encyclopedia of Applied and Computational Mathematics
Edited books
Encyclopedia of Applied and Computational Mathematics
Encyclopedia of Applied and Computational Mathematics
Posters
J. Sundnes, S. Wall, V. Timmermann and A. Tveito
Mechano-electric feedback as a source of ectopic activity
Gordon Research Conference on Arrhythmia Mechanisms, Lucca, Italy
2005
Technical reports
B. F. Nielsen, T. S. Ruud, G. T. Lines and A. Tveito
Optimal Monodomain Approximations of the Bidomain Equations
K. Mardal, B. F. Nielsen, X. Cai and A. Tveito
An Order Optimal Solver for the Discretized Bidomain Equations
1991
Technical reports
E. Arge, M. Dæhlen and A. Tveito
Computing Smooth Box Spline Approximations to Regularly Scattered Data
M. Dæhlen, H. P. Langtangen and A. Tveito
Some Research Projects in Industrial Mathematics