Authors | Å. Telle, S. Wall and J. Sundnes |
Editors | A. Tveito, M. E. Rognes and K. Mardal |
Title | Modeling Cardiac Mechanics on a Sub-Cellular Scale |
Afilliation | Scientific Computing |
Project(s) | Department of Computational Physiology |
Status | Published |
Publication Type | Book Chapter |
Year of Publication | 2021 |
Book Title | Modeling Excitable Tissue: The EMI Framework |
Volume | 7 |
Edition | 1 |
Chapter | 3 |
Pagination | 28-43 |
Date Published | 11/2020 |
Publisher | Springer International Publishing |
Place Published | Cham |
Abstract | We aim to extend existing models of single-cell mechanics to the EMI framework, to define spatially resolved mechanical models of cardiac myocytes embedded in a passive extracellular space. The models introduced here will be pure mechanics models employing fairly simple constitutive laws for active and passive mechanics. Future extensions of the models may include a coupling to the electrophysiology and electro-diffusion models described in the other chapters, to study the impact of spatially heterogeneous ion concentrations on the cell and tissue mechanics. |