AuthorsÅ. Telle, S. Wall and J. Sundnes
EditorsA. Tveito, M. E. Rognes and K. Mardal
TitleModeling Cardiac Mechanics on a Sub-Cellular Scale
AfilliationScientific Computing
Project(s)Department of Computational Physiology
StatusPublished
Publication TypeBook Chapter
Year of Publication2021
Book TitleModeling Excitable Tissue: The EMI Framework
Volume7
Edition1
Chapter3
Pagination28-43
Date Published11/2020
Publisher Springer International Publishing
Place PublishedCham
Abstract

We aim to extend existing models of single-cell mechanics to the EMI framework, to define spatially resolved mechanical models of cardiac myocytes embedded in a passive extracellular space. The models introduced here will be pure mechanics models employing fairly simple constitutive laws for active and passive mechanics. Future extensions of the models may include a coupling to the electrophysiology and electro-diffusion models described in the other chapters, to study the impact of spatially heterogeneous ion concentrations on the cell and tissue mechanics.

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