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V. Charwat, B. Charrez, B. A. Siemons, H. Finsberg, K. H. Jæger, A. G. Edwards, N. Huebsch, S. Wall, E. Miller, A. Tveito et al.

Validating the Arrhythmogenic Potential of High-, Intermediate-, and Low-Risk Drugs in a Human-Induced Pluripotent Stem Cell-Derived Cardiac Microphysiological System

ACS Pharmacology & Translational Science 5, no. 8 (2022): 652-667.
Journal Article
2022
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N. Huebsch, B. Charrez, G. Neiman, B. Siemons, S. C. Boggess, S. Wall, V. Charwat, K. H. Jæger, D. Cleres, Å. Telle et al.

Metabolically driven maturation of human-induced-pluripotent-stem-cell-derived cardiac microtissues on microfluidic chips

Nature Biomedical Engineering 6, no. 4 (2022): 372-388.
Journal Article
2022
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K. H. Jæger, A. G. Edwards, W. R. Giles and A. Tveito

Arrhythmogenic influence of mutations in a myocyte‑based computational model of the pulmonary vein sleeve

Nature Scientific Reports 12 (2022): 7040.
Journal Article
2022
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K. H. Jæger and A. Tveito

Deriving the Bidomain Model of Cardiac Electrophysiology From a Cell-Based Model; Properties and Comparisons

Frontiers in Physiology 12 (2022): 811029.
Journal Article
2022
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02 January 2023
Deputy Director Kyrre Lekve (Photo: Simula/Bård Gudim)

Kyrre Lekve is Interim Managing Director

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18 March 2016

Her er Simulas 14 eksempler på egen suksess med dagens organisasjonsform

BAKGRUNN: 1. Simula opprettet Kalkulo og inngikk et omfattende industrisamarbeid med Norsk Hydro etterfulgt av Statoil. Samarbeidet har gitt inntekter på nærmere 150 MNOK til Simula. 2.
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2022

Journal articles

V. Charwat, B. Charrez, B. A. Siemons, H. Finsberg, K. H. Jæger, A. G. Edwards, N. Huebsch, S. Wall, E. Miller, A. Tveito et al.

Validating the Arrhythmogenic Potential of High-, Intermediate-, and Low-Risk Drugs in a Human-Induced Pluripotent Stem Cell-Derived Cardiac Microphysiological System

ACS Pharmacology & Translational Science 5, no. 8 (2022): 652-667.
Status: Published
N. Huebsch, B. Charrez, G. Neiman, B. Siemons, S. C. Boggess, S. Wall, V. Charwat, K. H. Jæger, D. Cleres, Å. Telle et al.

Metabolically driven maturation of human-induced-pluripotent-stem-cell-derived cardiac microtissues on microfluidic chips

Nature Biomedical Engineering 6, no. 4 (2022): 372-388.
Status: Published
K. H. Jæger and A. Tveito

Deriving the Bidomain Model of Cardiac Electrophysiology From a Cell-Based Model; Properties and Comparisons

Frontiers in Physiology 12 (2022): 811029.
Status: Published
K. H. Jæger, A. G. Edwards, W. R. Giles and A. Tveito

Arrhythmogenic influence of mutations in a myocyte‑based computational model of the pulmonary vein sleeve

Nature Scientific Reports 12 (2022): 7040.
Status: Published
2021

Journal articles

K. H. Jæger, A. G. Edwards, W. R. Giles and A. Tveito

A computational method for identifying an optimal combination of existing drugs to repair the action potentials of SQT1 ventricular myocytes

PLoS Computational Biology 17 (2021): e1009233.
Status: Published
K. H. Jæger, A. G. Edwards, W. R. Giles and A. Tveito

From Millimeters to Micrometers; Re-introducing Myocytes in Models of Cardiac Electrophysiology

Frontiers in Physiology 12 (2021): 763584.
Status: Published
K. H. Jæger, V. Charwat, S. Wall, K. E. Healy and A. Tveito

Identifying drug response by combining measurements of the membrane potential, the cytosolic calcium concentration, and the extracellular potential in microphysiological systems

Frontiers in Pharmacology 11 (2021): 569489.
Status: Published
K. H. Jæger, S. Wall and A. Tveito

Computational prediction of drug response in short QT syndrome type 1 based on measurements of compound effect in stem cell-derived cardiomyocytes

PLoS Computational Biology 17, no. 2 (2021): e1008089.
Status: Published
K. H. Jæger, K. G. Hustad, X. Cai and A. Tveito

Efficient numerical solution of the EMI model representing the extracellular space (E), cell membrane (M) and intracellular space (I) of a collection of cardiac cells

Frontiers in Physics 8 (2021): 579461.
Status: Published

Book chapters

K. H. Jæger and A. Tveito

Derivation of a Cell-Based Mathematical Model of Excitable Cells

In Modeling Excitable Tissue: The EMI Framework, 1-13. Vol. 7. Cham: Springer International Publishing, 2021.
Status: Published