Glenn Terje Lines

P. Lakrisenko, P. Stapor, S. Grein, L. Paszkowski, D. Pathirana, F. Fröhlich, G. T. Lines, D. Weindl and J. Hasenauer

Efficient computation of adjoint sensitivities at steady-state in ODE models of biochemical reaction networks

PLOS Computational Biology

A. H. Erhardt, K. Tsaneva-Atanasova, G. T. Lines and E. A. Martens

Editorial: Dynamical Systems, PDEs and Networks for Biomedical Applications: Mathematical Modeling, Analysis and Simulations

Frontiers in Physics

T. R. Karlsen, M. B. Olsen, X. Y. Kong, K. Yang, A. Quiles-Jiménez, P. Kroustallaki, S. Holm, G. T. Lines, P. Aukrust, T. Skarpengland, M. Bjørås, T. B. Dahl, H. Nilsen, I. Gregersen and B. Halvorsen

NEIL3-deficient bone marrow displays decreased hematopoietic capacity and reduced telomere length

Biochemistry and Biophysics Reports

A. M. Bruaset, G. T. Lines and J. Sundnes

Data aggregation and anonymization for mathematical modeling and epidemiological studies

Smittestopp - A Case Study on Digital Contact Tracing

J. Skogestad, G. T. Lines, W. E. Louch, O. M. Sejersted, I. Sjaastad and J. M. Aronsen

Evidence for heterogeneous subsarcolemmal Na+ levels in rat ventricular myocytes

AJP-Heart and Circulatory Physiology

C. Jarvis, G. T. Lines, J. Langguth, K. Nakajima and X. Cai

Combining algorithmic rethinking and AVX-512 intrinsics for efficient simulation of subcellular calcium signaling

International Conference on Computational Science (ICCS 2019)

G. T. Lines, L. Paszkowski, L. Schmiester, D. Weindl, P. Stapor and J. Hasenauer

Efficient computation of steady states in large-scale ODE models of biochemical reaction networks

8th IFAC Conference on Foundations of Systems Biology in Engineering

T. R. Kolstad, J. van den Brink, N. MacQuaide, P. K. Lunde, M. Frisk, J. M. Aronsen, E. S. Norden, A. Cataliotti, I. Sjaastad, O. M. Sejersted, A. G. Edwards, G. T. Lines and W. E. Louch

Ryanodine Receptor Dispersion Disrupts Ca2+-Release in Failing Cardiac Myocytes

eLife

A. Tveito, M. Maleckar and G. T. Lines

Computing Optimal Properties of Drugs Using Mathematical Models of Single Channel Dynamics

Computational and Mathematical Biophysics

M. Maleckar, A. G. Edwards, W. E. Louch and G. T. Lines

Studying dyadic structure–function relationships: a review of current modeling approaches and new insights into ca2+ (mis) handling

Clinical Medicine Insights: Cardiology

T. Mäki-Marttunen, G. T. Lines, A. G. Edwards, A. Tveito, A. M. Dale, G. T. Einevoll and O. A. Andreassen

Pleiotropic effects of schizophrenia-associated genetic variants in neuron firing and cardiac pacemaking revealed by computational modeling

Translational Psychiatry

A. Tveito, K. H. Jæger, G. T. Lines, Ł. Paszkowski, J. Sundnes, A. G. Edwards, T. Mäki-Marttunen, G. Halnes and G. T. Einevoll

An Evaluation of the Accuracy of Classical Models for Computing the Membrane Potential and Extracellular Potential for Neurons

Frontiers in Computational Neuroscience

M. Maleckar, A. G. Edwards, W. Louch and G. T. Lines

Studying dyadic structure-function relationships: a review of current modeling approaches and new insights into Ca2+ (mis)handling

Clinical Medicine Insights: Cardiology

G. T. Lines, B. L. de Oliveira, O. Skavhaug and M. Maleckar

Simple t-wave metrics may better predict early ischemia as compared to st segment

IEEE Transactions on Biomedical Engineering

A. Tveito, G. T. Lines, A. G. Edwards and A. D. McCulloch

Computing rates of Markov models of voltage-gated ion channels by inverting partial differential equations governing the probability density functions of the conducting and non-conducting states

Mathematical Biosciences

G. T. Lines, B. L. de Oliveira, O. Skavhaug and M. Maleckar

Simple T wave metrics may better predict early ischemia as compared to ST segment

IEEE Transactions on Biomedical Engineering

A. Tveito and G. T. Lines

Computing characterizations of drugs for ion channels and receptors using Markov models

J. Langguth, M. Sourouri, G. T. Lines, S. Baden and X. Cai

Scalable heterogeneous CPU-GPU computations for unstructured tetrahedral meshes

IEEE Micro

M. Maleckar, G. T. Lines, J. Koivumäki, K. Calloe and J. Cordeiro

NS5806 Partially Restores APD But Fails to Ameliorate Ca2+ Transient Dysfunction in a Computational Model of Canine Heart Failure

Europace 2014

M. Maleckar, G. T. Lines and J. Koivumäki

Ca2+-Transient Dysfunction and Ion Channel Therapy: What Can We Gather From a Computational Model of Canine Heart Failure?

G. T. Lines, O. M. Lysaker and B. F. Nielsen

Observability of Ischemia and the Need for Patient Specific Geometrical Models in Inverse ECG

Computing in Cardiology, Zaragoza, Spain

G. T. Lines and X. Cai

Elements of Scientific Computing

3-day intensive course given at National University of Defence Technology, China, October 16-18

J. E. Hake, W. E. Louch, K. Haugen, I. Sjaastad, O. M. Sejersted, A. D. McCulloch, A. P. Michailova and G. T. Lines

A Stochastic Model of the Ryanodine Receptor Featuring Coupled Gating and Competitive Binding of Luminal and Cytosolic Ca2+ and Mg2+

G. T. Lines and J. Sundnes

Computer Simulations of the Heart

Simula Research Laboratory - by thinking constantly about it

J. E. Hake and G. T. Lines

Modelling the Mesoscopic Length Scale of EC Coupling: the Diadic Cleft

Invited talk at 'European Conference on Mathematical and Theoretical Biology'

J. E. Hake and G. T. Lines

Stochastic Binding of Ca2+ Ions in the Dyadic Cleft Continuous Vs Random Walk Description of Diffusion

Presentation at ICIAM 07

J. E. Hake and G. T. Lines

Stochastic Binding of Ca2+ Ions in the Dyadic Cleft Continuous Vs Random Walk Description of Diffusion

Poster presentation at 5th Annual CHFR Symposium

G. T. Lines

Cardiac Computing at Simula

Talk at CBC Workshop on Biomedical Computing

G. T. Lines

Overview of the Cardiac Computations Project

Talk at CBC, Seminar on Electrophysiology Modeling

X. Cai and G. T. Lines

Full-Scale Simulation of Cardiac Electrophysiology on Parallel Computers

Numerical Solution of Partial Differential Equations on Parallel Computers

M. Hanslien, J. Sundnes, G. T. Lines and A. Tveito

Simulating Electrical Activity in the Heart

Presented at St Jude Medical, Stockholm, Sweeden

B. F. Nielsen, O. M. Lysaker, X. Cai, K. Mardal, C. Tarrou, M. C. MacLachlan, J. Sundnes, G. T. Lines and A. Tveito

Computational Issues in Heart Modeling

Presented at the Johann Radon Institute for Computational and Applied Mathematics, Linz, Austria

B. F. Nielsen, T. S. Ruud, G. T. Lines and A. Tveito

Optimal Monodomain Approximations of the Bidomain Equations

X. Cai, G. T. Lines and A. Tveito

Parallel Solution of the Bidomain Equations With High Resolutions

Parallel Computing: Software Technology, Algorithms, Architectures & Applications

T. K. Nilssen, L. Ingebrigtsen, M. Hanslien, G. T. Lines and A. Tveito

Resolution Requirements for a 1D Monodomain Model for Simulating

J. Sundnes, G. T. Lines and A. Tveito

Challenges in Mathematical Models of the Heart

Presented at the SIAM Annual meeting, Portland, Oregon

X. Cai, A. M. Bruaset, H. P. Langtangen, G. T. Lines, K. Samuelsson, W. Shen, A. Tveito and G. Zumbusch

Performance Modeling of PDE Solvers

Advanced Topics in Computational Partial Differential Equations - Numerical Methods and Diffpack Programming

J. Sundnes, G. T. Lines, P. Grøttum and A. Tveito

Electrical Activity in the Human Heart

Advanced Topics in Computational Partial Differential Equations - Numerical Methods and Diffpack Programming

G. T. Lines, X. Cai and J. Sundnes

Parallel Algorithms for Simulating the Electrical Activity of the Heart

Presented at the Dagstuhl seminar Challenges in computational science and engineering

X. Cai, G. T. Lines and A. Tveito

Toward Extremely High-Resolution Simulation of Human Heart

Talk at the ParCo 2003 Conference, 2 - 5 September 2003, Dresden, Germany

B. F. Nielsen, G. T. Lines and A. Tveito

Determining the Size and Location of a Myocardial Infarction; a Scientific Computing Framework

Presented at the European Conference on Numerical Mathematics and Advanced Applications, Prague, Czech Republic

G. T. Lines, B. F. Nielsen, A. Tveito, J. Sundnes, P. Grøttum, X. Cai and K. Mardal

Computing the Electrical Activity in the Human Heart

Presented at the Centre of Mathematics for Applications, Oslo

G. T. Lines, J. Sundnes, A. Tveito, X. Cai, K. Mardal and A. M. Bruaset

Diffpack Simulation of the Electrical Activity in the Heart

Invited minisymposium talk at the 20th CAD-FEM User's Meeting, Friedrichshafen, Germany

G. T. Lines, X. Cai and A. Tveito

A Parallel Solution of the Bidomain Equations Modeling the Electrical Activity of the Heart

J. Sundnes, G. T. Lines, K. Mardal and A. Tveito

On Numerical Techniques for the Bidomain Model

Presented at the SIAM Annual meeting, San Diego, California

J. Sundnes, G. T. Lines and A. Tveito

An Investigation of Different Solvers for Stiff ODE Systems

J. Sundnes, G. T. Lines and A. Tveito

Efficient Solution of ODEs Modeling Electrical Activity in Cardiac Cells

DIFTA seminar, Norwegian University of Science and Technology

G. T. Lines

Simulating the Electrical Activity in the Heart - a Bidomain Model of the Ventrciles Embedded in a Torso

X. Cai, A. M. Bruaset, H. P. Langtangen, G. T. Lines, K. Samuelsson, W. Shen, A. Tveito and G. Zumbusch

Performance Modeling of PDE Solvers

G. T. Lines and T. Kavli

The Equivalence of Spline Models and Fuzzy Logic Applied to Model Construction and Interpretation

Neural Adaptive Control Theory